Antibiotic
Unasyn (sultamicilin) cannot be taken with food as this will affects the bioavailability / absorption of Unasyn in the body.
A. True
B. False
False
1. Clinical studies with Dynastat were conducted up to ____ days of treatment.
2. Based on Dynastat Malaysia PI, there is limited clinical experience beyond ____ days.
1. 7 days.
2. 3 days
Where is Pfizer New York located?
Manhattan City
Vfend is a broad spectrum, triazole antifungal agent and is indicated in adults and children aged ____.
2 years and above.
What is the generic name for Augmentin and who is the manufacturer?
amoxicilin + clavulanic acid
GlaxoSmithKline (GSK)
What is the recommended duration for Tygacil in treating cSSSI and cIAI?
5-14 days
Reference: Tygacil PI / pg2 / section 4.2
In SEDCOM study showed median time to extubation was _____days shorter in dexmedetomidine treated patient vs Midazolam treated patient.
1.9 days
(Reference: Precedex / Unique Sedation Profile eDA)
Dato' Sri Ismail Sabri bin Yaacob ialah Perdana Menteri yang keberapa di Malaysia?
Ke.9
What Candida species was excluded in Reboli study?
Candida krusei
(Reference: Reboli clinical paper pg.2473)
What is the dosing regimen for Caspofungin in adult patient weighing <80kg?
Loading dose:____________
Maintenance dose: _______________
Loading dose: 70mg on Day 1
Maintenance dose: 50mg once daily
Zinforo demonstrates clinical activity against MRSA as a results of its strong affinity for which penicilin-binding proteins?
PBP2a
(Reference: Zinforo eDA / Microbiology 4th slide)
What does PADIS stand for?
Pain
Agitation
Delirium
Immobility
Sleep
What does a palaeontologist study for?
Fossils
In Herbrecht study, Vfend demonstrated _______ higher survival rate over 12 weeks vs amphotericin B.
12.9%
(Reference: Vfend eDA / Treatment for IA)
What is the Tedizolid recommended duration of treatment for ABSSSI?
6 days
(ABSSSI: Acute bacterial skin & skin structure infection)
MIC breakpoints against Enterobacteriaceae and P. aruginaso for Zavicefta have been established by the EUCAST as
Susceptible at ________mg/L
Resistant at ________mg/L
>8mg/L (more than)
Reference: Zavicefta PI pg 14
What is Dynastat dosing regimen for renal impairment patient as below:
1.CrCL 30-80mL/min : ______________
2. CrCL <30mL/min : _______________
1. No dosage adjustment
2. Dynastat should be initiated at the lowest recommended dose (20mg)and the patient's kidney function closely monitored.
Paris
In SECURE study, the primary endpoint-All cause mortality from first dose of study drug to day 42 in ITT population was _____% for isavuconazole & _______% for voriconazole.
19% for isavuconazole
20% for voriconazole
(Reference: SECURE clinical paper pg765)
VRE infection
NP
cSSSI including diabetic foot infections
Uncomplicated skin and skin structure infections
CAP
In management of acute pain, how much is the reduction of daily opoid requirement after Dynastat is used concomitantly?
20% - 40%
(Dynastat PI pg2)
Who created penicilin and what is Penicilin made from?
Alexander Fleming
Penicilium chrysogenum
In VITAL study, what is the three most often identified Mucorales?
1.
2.
3.
1. Rhizopus oryzae
2. Mucor spp
3. Rhizomucor spp
(Reference: VITAL clinical study pg 831)