messaging
enzyme replacement therapy for the treatment of genetically determined sucrase deficiency, which is part of congenital sucrase isomaltase deficiency
What is Sucraid
Pediatric GI from Children's Hospital LA and paid consultant for QOL
Who is Dr. Danialifar
Doctor in Chicago, busy practice non-academia, paid consultant for QOL
Who is Dak Patel
Physicians Associate in a GI office in Florida, paid consultant for QOL
Who is Kaitlin Colella
Location of article from Medical College of Georgia on "Sucrase-isomaltase deficiency causing persistent bloating and diarrhea in an adult female"
What is Cureus
Easy, free, non-invasive way to assess sucrose absorption
What is C13 Sucrose Breath test
Age of patient in this case and when did they first see a GI
What is 16 and 9
age and gender of patient
what is 24 year old female
Chronic diarrhea, postprandial bloating, cramping and abdominal pain
what are symptoms
age of patient in study
Percentage of patients that became asymptomatic 7/10 days on normal diet with addition of Sucraid
What is 81%
Diet interventions that were tried and failed
What are low lactose and low FODMAP
Cereal, soda, caffeine
what are foods that bring on symptoms
fecal elastase, EGD with biopsies but not disac, and colonoscopy
Lab tests, stool studies, EGD normal for celiac, H-pylori, microscopic colitis, IBD. HMBT for SIBO positive, repeat EGD with Disac
What are extensive lab tests
Why grandparents or parents also suffer from postprandial symptoms
what is a genetic component
Who else had similar symptoms without a diagnosis
Grandmother
Rifaximin, EGD, Referral to dietitian, low-FODMAP diet
what are tried and failed therapy
Pepto-Bismol, caraway oil, dicyclomine, hyoscyamine, rifaximin, and cholestyramine
what are tried and failed therapies
Rifaximin and Omeprazole
what are failed treatments
Gas/Bloat/nausea after eating for greater than 6 months
Result of Sucraid Therapy
What is resolution of Symptoms
Carbon 13 and sucraid
What are the tools to aid in diagnosis
Formed stool in 3 weeks, symptom free at 12 months
What are the results once on Sucraid
What are results from disac biopsy