Pharmacokinetic
What is the active ingredient in AIMOVIG?
erenumab
monoclonal antibody
Dosage and strength
Auto injection pens and prefilled syringes
70 mg/mL and 140 mg/mL
when was AIMOVIG approved?
May 2018
What are some common side effects?
-muscle cramps
-flu like symptoms
-injection site reactions
can i afford it?
AIMOVIG cost about $811.75/ mL
AIMOVIG Belongs to what class?
calcitonin gene-related peptide (CGRP) receptor blocker
How is AIMOVIG administered?
subQ in the belly
front thighs
or back of upper arms
Place in therapy
-Not first line
- Migraine prophylaxis
-Use when other drugs can't be used or not effective in reducing the migraine
What are some serious side effects?
constipation
new or worsened high BP
Anaphylaxis reactions
How is it stored?
need to be refrigerated at 2 to 8 degrees C
Is AIMOVIG metabolized in the Liver?
AIMOVIG is not a substrate of CYP 450
It is break down in some cells in the body
Who can benefit from it?
Adult with episodic or chronic migraine who can't take other medications or those who did not find any relief from other medications
No pediatric, pregnant and lactating women
What is the elimination half-life of AIMOVIG?
28 days