Case Study
Enzymes during pregnancy
Adolescent substance abuse
Readings
Random from presentation
100

Did this story end happily?

Yes

100

Name two enzymes that increase activity during pregnancy?

P450 (CYP), CYP34a, Cyp2d6, Cyp3cc9, CYp2a6, Ugt1a4, UGT2B7

100

What percentage of 12-20 year olds report binge drinking last month?

60.2%

100

Alcoholism is common to all socioeconomic groups T/F

True

100

Is there a cure for drug addiction?

No, only management 

200

What was the age of the mother in our case study?

45 years old

200

Name two enzymes that decrease in activity during pregnancy?

Cyp1a2 and Cyp2c19

200

What is more likely than parental substance abuse to lead to adolescent substance use?

Social contagion (siblings and peers)

200

Substance abuse is a weakness of character? T/F

False. Substance abuse is a disease

200

Why is drug use so dangerous to adolescents?

Their prefrontal cortex is still developing.  They have a lower impulse control than adults.  

300

What was the son in our case study addicted to?

Cannabis and Heroin

300

Does Cholinesterase increase or decrease in activity during pregnancy?

decreases

300

8th grader drug use is up by how much from 2016-2020?

61%

300

What is the most common reason for children being placed into the foster system?

Substance abusing parents/guardians.

300

Name two community resources.

Barth Clinic, Northpoint, Comprehensive healthcare, Yakima county

400

What drug did the mother use to forget her son's problems?

Alcohol

400

Which illicit drug does cholinesterase metabolize?

Cocaine

400

What percentage of OD deaths are aged 15-24?

11.2%

400

Parental substance abuse increases their risk for . . . (+100 for both)

Psychiatric disorders

Poor parenting behaviors

400

Relapse rates for drug addiction are similar to what? 

Chronic medical illness relapse. 

500

What was the mother's comment on the experience she had at the hospital?

"very, very, nice"

500

Why is the enzyme that metabolizes nicotine increased during pregnancy?

The increased estrogen during pregnancy causes the enzyme to increase.  

500

How many teens aged 12-17 met the criteria for Alcohol use disorder in the last year?

407,000

500

What adverse effects are siblings of substance abusers likely to expereince?

Depression and lack of social support.

500

What is the most commonly abused substance in teens and young adults?  

Alcohol