Treatment for acute ischemic stroke in patients with sickle cell disease
Exchange transfusion and aspirin (accept exchange transfusion)
*Exchange transfusion also used in treatment of severe acute chest syndrome
A 40 year old morbidly obese male with no significant past medical history or recent infection presents with bilateral edema. Labs reveal hypoalbuminemia and profound hyperlipidemia. 24 hr urine reveals 3.8 g protein. What is the most likely etiology of his renal disease?
FSGS
*Nephrotic syndrome associations:
FSGS: HIV, morbid obesity
Membranous Nephropathy: Hep B, C, syphillis, SLE, drugs, cancers
Minimal change: Post infection
DM renal disease: slowly progressive with long standing DM
The most effective drug for intermittent claudication
Cilostazol
This CT and analogous food item represent which disease?
Autoimmune pancreatitis
*Sausage shaped pancreas
Type 1 AIP associated with IgG4-related diseases: Sjögren syndrome, PSC, bile duct strictures, autoimmune thyroiditis, retroperitoneal fibrosis, sclerosing sialoadenitis, interstitial nephritis.
Type 2 AIP: associated with chronic pancreatitis and IBD, less likely to include elevated IgG4 levels
According the the song “Santa Clause is Coming to Town,” how many times does Santa check his list?
Twice
Pre-op hemoglobin transfusion goal in patients with sickle cell disease
10
This elective surgery is associated with a high risk of calcium oxalate stones
Roux-en-y gastric bypass
(Accept bariatric surgery, short gut syndrome, bowel resection)
"Funny" channel inhibitor used in patients with an EF <35% who are in sinus rhythm with a heart rate >70 despite maximal beta blocker therapy
Ivabradine
Name 2 indications for cholecystectomy in patients with a gallbladder polyp
Polyp >/= 1 cm
Polyp >/= 8 mm with primary sclerosing cholangitis
Polyp of any size in the presence of gallstones or biliary colic
In a rather morbid song written in the 70s, which family member gets run over by a reindeer?
Grandma
A 25 year old male presents with fatigue, yellow skin and a palpable spleen. Labs reveal anemia, reticulocytosis, elevated LD, indirect hyperbilirubinemia and spherocytes on peripheral smear. Which test should you order to differentiate between 2 likely diagnoses?
Direct antiglobulin test
(Accept coombs test, DAT test)
*Need to differentiate between hereditary spherocytosis and autoimmune hemolytic anemia
This disorder is often responsible for neurological symptoms after or during dialysis and is thought to be due to osmotic shifts causing transient cerebral edema
Dialysis disequilibrium syndrome
Name one cardiac condition with paradoxical splitting (split S2 with expiration)
LBBB, HCM and severe AS
Order this diagnostic test for a patient with cirrhosis who becomes dyspneic and hypoxemic sitting up with symptom relief when lying down
Transthoracic contrast echocardiogram (accept contrast echo)
*Patient has hepatopulmonary syndrome and symptoms are consistent with platypnea-orthodeoxea syndrome
This song, released in 1994, is the most digitally downloaded/streamed Christmas song of all time
All I Want for Christmas is You
A mixing study
*Missing factor vs factor inhibitor
Likely etiology for the following labs in a hypovolemic patient:
Serum Sodium: 128
Serum Osms: LOW
Urine Sodium: LOW
Negative urine anion gap
GI Losses (Diarrhea)
Urine anion gap = Na + K - Cl
NEGATIVE in GI LOSSES
POSITIVE in RENAL LOSSES
Syndrome associated with a pseudo-RBB pattern and ST elevations in V1-V3
Brugada syndrome
A patient with primary biliary cholangitis requires a liver biopsy if these 2 criteria are met
Alkaline phosphatase level ≥1.5× ULN
Positive antimitochondrial antibody titer OR positive sp100 or gp210 if antimitochondrial antibody is negative
(Accept elevated Alk phos and positive AMA)
Jingle Bells
An 88 year old presents with fatigue, fever, night sweats and weight loss. Labs reveal anemia, thrombocytopenia, leukocytosis and the following peripheral smear. What is the most likely diagnosis?
Primary myelofibrosis
Bone mineral disorder seen in chronic kidney disease that results from abnormal bone turnover due to secondary hyperparathyroidism or complications of hyperparathyroidism treatment
Renal osteodystrophy
Osteitis fibrosa cystica: inadequate tx of secondary hyperPTH
Adymanic bone disease: excess tx of secondary hyperPTH
The 2 most common structural heart diseases associated with syncope
Aortic stenosis and hypertrophic cardiomyopathy
What are the 2 indications to screen for hepatocellular carcinoma in patients with primary biliary cholangitis?
Male sex and presence of cirrhosis
Written in the 1940s, critics say the lyrics of this popular jingle are suggestive of harassment while others argue that it represents breaking the cultural expectations of the songs time
Baby it's Cold Outside