MacGas
CVS
Plants are the lungs of the earth
Other organs
PK Tidbits
100
The minimum alveolar concentration needed to prevent 50% of patients from moving to surgical stimuli
What is MAC?
100
Kidney liver and gut all experience this type of change in blood flow the context of inhaled volatiles
What is a decrease in blood flow?
100
What happens to bronchiolar smooth muscle with volatiles?
Relaxation
100
This inhaled gas does not trigger malignant hyperthermia
What is Nitrous
100
The technique in which one delivers a higher Fi of inhaled agent than what is needed for MAC to facilitate faster onset
What is overpressurization?
200
The oncentration of gas in the alveoli needed to suppress response to verbal command in 50% patients (roughly 1/3MAC)
What is MAC-awake?
200
The phenomenon where vasodilation causes blood to go from one segment of the myocardium to another, possibly undesirably
What is coronary steal?
200
Tacrolimus comes from the bark of this tree
What is the Yew tree?
200
This is the most likely volatile to cause carbon monoxide production in desiccated CO2 absorbants
Desflurane
200
A substance with low vapor pressure, high boiling point, liquids at room temperature
What is a volatile?
300
Hyperthermia, chronic alcohol use and hypernatremia all share this in common when it comes to volatile agents
What are factors that increase MAC?
300
A volatile that causes increased cardiac arrythmogenicity particulalry when given in conjunction with epinephrine
What is halothane
300
Atropine is one of the common toxins derived from this plant
What is Atropa belladona (or deadly nightshade?)
300
This gas oxidizes the cobalt atom of vitamin B12 and can theoretically cause agranulocytosis
What is Nitrous oxide
300
The percentage dialed into this vaporizer must be adjusted at high altitudes to maintain MAC
What is desflurane?
400
The phenomenon in which despite decreasing CMRO2, there is increased blood flow.
What is decoupling?
400
Ondansetron, Desflurane and Haldol are among the drugs that can impact this ECG parameter
What is QTc
(Desflurane > Sevoflurane)
400
This gas causes a slight increase in PVR, in contrast to other volatile agents
What is nitrous oxide?
400
A theoretical substance from degradation of barium hydroxide absorber and sevoflurane that can cause renal injury
What is compound A?
400
This physiologic factor, when lower, will decrease the solubility of volatile gasses.
What is the hematocrit?
500
What happens to MAC per decade of age?
6% decrease per decade of life
500
All volatiles decrease sympathetic outflow except this one
What is desflurane?
500
How much MAC is required to suppress hypoxic response to ventilatory drive by 25-85%?
0.1 MAC is sufficient
500
A metabolic breakdown substance of halothane that modifies liver proteins that results in autoimmune hepatitis
What is trifluoroacetic acid?
500
When this is low in patients, the solubility of volatiles decreases.
What is a hematocrit?