Gen 1
The technology that sequences DNA via chemical degradation?
Maxam-Gilbert
The amplification step used in Illumina Sequencing
Bridge Amplification
Technology based on measuring the change in (voltage/electrical charge) flowing across the membrane
Oxford Nanopore
The year that Maxam-Gilbert sequencing method was published
1977
The poet who authored the poem we used in 'Poem Assembly' project
Robert Frost
The first technology to do sequencing by synthesis
Sanger sequencing
Sequencing by ligation
SOLiD
What is a major bioinformatic challenge with 3rd generation sequencing?
High sequencing error rate
The year that the Human genome project began in
1990
The serial killer that was finally apprehended through use of forensic genealogy
Golden State Killer/Joseph James DeAngelo
Another name for chain-terminating nucleotides utilized in Sanger sequencing.
ddNTPs
System that detects synthesis by measuring change in pH
Ion Torrent
The organism that the Oxford Nanopore minION was trained on to detect methylated DNA
E. coli
The year that the first human chromosome (22) was sequenced
1999
The genome sequencing company that recently had a huge data breach of 6.9 million customers
23andMe
The first widely adopted method for DNA sequencing
Maxam-Gilbert
Amplification step in 454, applied Biosystems tech, and other NextGen sequencing technologies
Emulsion PCR
Smallest nanopore platform available on the market
Min-Ion
The year Watson, Crick, Wilkins and Franklin published a paper on discovery of the structure of DNA
1953
Common file format that delivers both a genomic sequence and a Phred score
FastQ file
The visual output for Sanger sequencing
Chromatogram
Quantity of ligation cycles needed to complete extension of the primer during SOLiD sequencing
7
Optical guidance system used in the SMRT technology (looking for full name, not acronym)
Zero-Mode Waveguide
The year that sequenced DNA was first used as a part of forensic genealogy to make a conviction in a cold case
2019
The type of sequencing technique that can help with the heterogeneous nature of cancer
scSeq (single cell sequencing)