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200

What is the universal gas constant (R)?

8.314 J mol-1 K-1 or 0.08206 L atm mol-1 K-1

200

What is the degree of degeneracy of the ground state particle in a 3D box? (Prof. Wilson, I'm sorry if the answer is wrong.)

1

200

For the following diagram, match the letter with the correct corresponding drug types .

  • Agonist

  • Partial Agonist

  • Inverse Agonist

  • Antagonist 

  • Resting State 




  • A /C = Resting State + Antagonist

  • B = Full Agonist 

  • D = Inverse Agonist

  • E = Partial Agonist

200

Differentiate between Type 1 and Type 2 Diabetes?

Type 1: Immune system mistakenly attacks the beta cells in the pancreas, preventing insulin secretion

Type 2: Body cells and receptors develop resistance to insulin 

400

What is the the Henderson-Hasselbalch equation

pH = pKa + log([A-]/[HA])

400

What is the sequence of amino acids in the following polypeptide?


Tyr Gly Gly Phe Leu

400

What is a “spider” scaffold?

a molecule core that allows a variation of functional groups to surround it to find multiple receptor-binding sites

400

Write out the Michaelis-Menten's Equation


600

Consider this equilibrium system:

CO(g) + Fe3O4(s) ⥫⥬ CO2(g) + 3FeO(s)

How does the equilibrium position shift as a result of CO being added?

Equilibrium position shifts toward products

600

What is the name of this experiment?


Stern Gerlach Experiment

600

How does high lipophilicity in a molecule influence its absorption, distribution, and metabolism?

  • Greater volume of distribution 

  • Higher absorption/permeability through the membrane.

  • Greater metabolic clearance 

600

A neurotransmitter receptor, when activated, coordinates influx of 4 [Cl-] and efflux of 1 [HCO3-]. It is known to be the major source of inhibition in the central nervous system. What is this neurotransmitter?

GABA is the neurotransmitter

800

What is the name of this mechanism?


Fischer-Esterification

800

The statements about adverse drug reactions are correct except: 

A. Dose-related ADRs are predictable based on a drug's pharmacology

B. Dose-unrelated ADR's are rare and unpredictable

C. Allergic reactions are an example of ADR's

D. ADR's can be predicted from animal studies

B. Dose-unrelated ADR's are rare and unpredictable

800

Isoprenaline Undergoes metabolism to give the inactive metabolite shown. Suggest why this metabolite is inactive.


One of the hydroxyl groups on the benzene group has been replaced with a methoxy group. This strips the functional group's ability to form hydrogen bonds to receptors.

800

What is the name of this protein? 


Green Fluorescent Protein

800

"I might swerve ____"


"bend that corner."