Bunnyaviridae basics
What is segmented negative-sense single-stranded RNA?
This is the genome type of Bunyaviridae viruses.
What is encephalitis?
This disease caused by the La Crosse virus is most common in children and results in inflammation of the brain.
What is blood-feeding?
Many bunyaviruses are transmitted to humans through this feeding behavior of arthropods.
What is the respiratory system?
Hantavirus Pulmonary Syndrome (HPS) affects this organ system.
What is endocytosis?
Bunyaviruses typically enter host cells through this cellular process.
What are mosquitoes and ticks?
The transmission of many Bunyaviruses occurs through these tiny arthropods.
What is a tick?
Crimean-Congo Hemorrhagic Fever is transmitted primarily by this arthropod.
What are rodents?
This mammal is the natural host of Hantaviruses, shedding the virus in urine, droppings, and saliva.
What is retinal damage?
This common symptom of Rift Valley Fever can lead to vision problems.
What is the cytoplasm?
Once inside the host, bunyavirus replication occurs primarily in this cellular compartment.
Pulmonary Syndrome (HPS) in humans.
What is Hantavirus?
This rodent-borne member of the Bunyaviridae family can cause Hantavirus Pulmonary Syndrome (HPS) in humans.
What are cattle and sheep?
The Rift Valley Fever virus primarily affects these two types of animals, though humans can also be infected.
What is Toscana virus?
The phlebovirus transmitted by sandflies that can cause a febrile illness.
What are the kidneys?
Hantaviruses causing Hemorrhagic Fever with Renal Syndrome (HFRS) primarily target these organs.
What is RNA-dependent RNA polymerase?
The three RNA genome segments of bunyaviruses are classified as L, M, and S. L codes for this essential enzyme.
What are the cytoplasm and Golgi apparatus?
Bunyaviridae viruses replicate in these cellular compartments.
What is Andes Virus?
This South American Hantavirus infection causes hemorrhagic fever with renal syndrome (HFRS).
What is Hantavirus?
Unlike most bunyaviruses, this virus is not transmitted by arthropods but instead by rodent contact.
What are platelets?
Severe Fever with Thrombocytopenia Syndrome (SFTS) is associated with a decrease in these blood cells.
What is RNA-dependent RNA polymerase?
The three RNA genome segments of bunyaviruses are classified as L, M, and S. L codes for this essential enzyme.
What is Rift Valley Fever Virus?
This hemorrhagic fever virus from the Bunyaviridae family was first identified in Kenya in 1930.
What is the deer mouse?
The primary host for Sin Nombre virus, which causes Hantavirus Pulmonary Syndrome in North America.
What is the La Crosse virus?
This virus, endemic in the United States, is transmitted by mosquitoes and named after a river in Wisconsin.
What is disseminated intravascular coagulation (DIC)?
This potentially fatal complication of Crimean-Congo Hemorrhagic Fever involves uncontrollable bleeding.
What are nucleocapsid proteins?
The genome segments are encapsulated by this type of protein for protection during viral assembly.