Mechanism of Action (MOA)
This drug class works by converting plasminogen to plasmin, leading to fibrin clot breakdown.
What are thrombolytic agents?
These drugs, including aspirin and clopidogrel, are used to prevent stroke and cardiovascular events by inhibiting platelet aggregation.
What are antiplatelet agents?
This common adverse effect of SSRIs and SNRIs is often a reason for medication discontinuation.
What is sexual dysfunction?
A 60-year-old man with a history of atrial fibrillation is started on clopidogrel after a stroke. What is the mechanism of action of this drug?
What is P2Y12 receptor inhibition?
To treat schizophrenia there are two classes of drugs that can be used that have what mechanisms of actions
What are atypical (D2 and serotonin antagonist) and typical antipsychotics (Dopamine D2 antagonists)?
Inhibits catechol-O-methyltransferase (COMT), prolonging dopamine effects
What is a COMT inhibitor?
These drugs, including donepezil, are used to treat this progressive neurodegenerative disease.
What is Alzheimer’s disease?
Dizziness, drowsiness occurs with the use of this drug.
What is Buspirone
A 25-year-old woman presents with treatment-resistant depression. Her psychiatrist prescribes a drug that blocks NMDA receptors. What is the drug?
What is esketamine?
This thrombolytic agent is commonly used for acute ischemic stroke, myocardial infarction, and pulmonary embolism.
What is alteplase?
This class of diuretics works by inhibiting the NaCl transporter in the distal convoluted tubule.
What are thiazide diuretics?
Phenytoin, Carbamazepine, Lamotrigine are used to treat this condition.
What are seizures
A major adverse effect of haloperidol and other typical antipsychotics, this syndrome includes rigidity, hyperthermia, and autonomic instability.
What is tardive dyskinesia?
A 70-year-old woman with multiple sclerosis is started on a new drug and develops flu-like symptoms. What drug is this?
What is Peginterferon beta-1a?
These drugs that perform serotonin receptor modulation can cause hallucinations and anxiety.
What is LSD, Psilocybin, DMT, Phencyclidine, THC, MDMA?
This drug increases dopamine release and is an NMDA antagonist
What is amantadine?
This benzodiazepine antagonist is used to reverse benzodiazepine overdose.
What is flumazenil?
Lithium toxicity can cause these two severe endocrine and renal side effects.
What are nephrotoxicity and hypothyroidism?
A 35-year-old patient taking an SSRI develops hyperreflexia, autonomic instability, and clonus after taking tramadol for pain. What syndrome is this?
What is serotonin syndrome?
This drug, inhibits aldehyde dehydrogenase, is the primary treatment for alcohol cessation.
What is Disulfiram?
This drug inhibits peripheral dopamine conversion
What is Carbidopa
Triptans and ergotamines are used to treat this neurological condition.
What are migraines?
The rare but serious condition Stevens-Johnson syndrome (SJS) is associated with these antiepileptics.
What are lamotrigine and carbamazepine?
A 47-year-old man is brought to the ED after a suspected overdose. He has respiratory depression, pinpoint pupils, and unconsciousness. What drug should be administered?
What is naloxone?
This atypical antidepressant is unique because it works as a dopamine and norepinephrine reuptake inhibitor and is used for smoking cessation.
What is bupropion?