Non-neoplastic disorders
WBC Morphology
Myeloproliferative Disorders
Lymphoproliferative Disorders
100
Increases in this cell linage can be seen in what conditions?
What are Bacterial Infections, Burns, Leukemoid Reactions.
100
This mature WBC has to substances in its granules. Name this cell and granule contents.
What is a Basophil that contains Heparin and Histamine granules.
100
A condition that has greater than 1,000,000/uL platelets, bruising and bleeding, negative JAK2 and Philadelphia Chromosome, and a normal hemoglobin and HCT?
What is Essential thrombocythemia?
100
You receive a smear that have several of these cells on them. What are these cells and how would you handle this sample?
What are smudge cells. I would add albumin and remake the slide.
200
Increases of this cell can be seen in what conditions?
What are Parasitic Infections, Allergies, or Asthma.
200
Name the WBC inclusion and what conditions are they seen in?
What are Dohle bodies seen in bacterial infections, burns, and May Heglin anomaly
200
A condition that has an increase of fibroblasts and increased collagen production, left shift, PH negative, hepatosplenomegaly and a dry BM tap.
What is Primary or Idiopathic Myelofibrosis.
200
What disorder has CD19, CD20, and CD103 positive cells with flow cytometry, dry BM tap, and the majority of the cells on the peripheral smear look like this? What stain would also be positive?
What is Hairy Cell Leukemia and cells stain TRAP Positive.
300
Greater than 10 of these cells can be seen in what conditions?
What are viral infections, CMV, or Mononucleosis.
300
What is this cell that is the last stage of mitosis?
What is a myelocyte?
300
An absolute RBC increase, low oxygen, increased EPO without a RBC mass is what condition?
What is a secondary polycythemia vera?
300
A patient presents with a large lymphadenopathy that is hard and painless. The physician told the patient upon biopsy that they have Hodgkins Lymphoma. What cell did the pathologist see on the biopsy smear?
What is a Reed Sternberg cell.
400
Increases in this cell in the peripheral smear can be seen in.
What is TB or chronic infections.
400
Name this cell usually seen in the BM and lymph nodes. What does it produce?
What is a Plasma cell that secretes antibodies or immunoglobulins.
400
What is the genetic marker that would aid in diagnosis for patients with increased RBC mass, hemoglobin and HCT increased, EPO normal. They may present with symptoms such as hypertension, Hypervelocity, and pruritus.
What is JAK2 mutation or JAK V617F.
400
A patient presented back pain. Lab results revealed increased protein serum and urine protein levels. The BM was hypercellular with many of these cells seen in the peripheral smear and this RBC formation. Name the condition?
What is Multiple Myeloma?
500
A shift to the left, > 50,000/uL WBC count, and a high/positive LAP score?
What is a leukemoid reaction.
500
What is this large 14-24 um granulocyte with prominent primary granules? 
What is a promyelocyte?
500
What is the translocation genetic marker that would be ordered if a patient presents with greater than 100,000/uL WBC count, shift to the left, LAP score low.
What is the BCR/ABL or 9/22 translocation, Philadelphia Chromosome.
500
A patient presented Raynausd's pheomenon and rouleaux and plasmacytoid lymphoctyes seen on the peripheral smear. An electorphoresis pattern shows the following results. What is this pattern indicate and what disorder is this?
What is a monoclonal antibody, and this is Waldenstrom's Macroglobulinemia.