DOC
uncomplicated UTI
nitrofurantoin and give pyridium (pain)
bone marrow depression (aplastic anemia)
chloramphenicol
tendon rupture + photosensitivity
fluroquinolones
and pytrazudamide (joint pain and photosensitivity)
what are the third generatio cephalosporins
can you promise a medication will be "safe" ?
NO - you can never promise it will be 100% safe 0 there will always be side effects
DOC for lymes
doxycycline
what causes black teeth in babies or pregnant women
tetracycylines
peripheral neuropathy
isoniazid --- what is the antidote? (pyridogzine)
what is the #1 drug to cause photosensitivity
tetracyclines
goal of nursing?
maximum benefit, minimum harm
TB treatment and prophylaxis
isoniazid
what causes red man syndrome if its too high
vancomycoin (>20)
all TB drugs cause hepatotoxicity EXCEPT
what are the 3 abx that can interfere and have a bleeding reaction
macrolides and cefotetan and sulfa
describe what ADME stands for
Absorption - entry into body --> blood stream (IV is fastest)
Distribution - how the drug is carried/transported
- free drug (percentage of the drug that is not bound to protein - this is what causes an effect)
- what crosses BBB (lipid soluble (phenytoin)
Metabolism - breakdown of drugs
Excretion
for P. jiroveci
sulfas (trimethoprim/sulfamethaxazole
what causes QT prolongation
macrolides (clarithromycin, azithromycin) and fluorquinolones
what do we use for TB in a patient with HIV
rifabutin (instead of rifampin)
dabtinomycin (muscle injury)
what is half life and is it dose dependent?
time for the blood level of the medication to decrease by 50%
no
half life x 5 = steady state
MRSA
vancomycin
what puts you at risk for serotonin syndrome
linezolid - if given with antidepressants, TSAs, MAOIs, SSRI, SNRI
what targets aerobic bacteria
monobactam
when is a patient fully treated for TB
- no more TB bacteria in the sputum
- no more colonies in the culture
what is an allergic reaction
and what is a iatrogenic reaction
immune response (antigen.antibody)
IGE mediated
not dose dependent
a disease caused by drugs