Dawnzera
First and only RNA targeted treatment for HAE
What is Dawnzera
Factor XIIa inhibitor
What is Andembry
wife is Shelly
what is Brian
minimum number of confirmed rsvps 6 business days before a speaker program
What is 3
Support program dedicated to help your patient start and follow the prescribed treatment plan with DAWNZERA including Patient Education Manager, Insurance Navigation, Affordability Programs, and Dawnzera Direct
What is IONIS EVERY STEP
Phase 3, randomized, double blind placebo controlled 6 month trial of patients aged 12 years and older with HAE type 1 and 2(N=90)
What is Oasis - HAE
Monoclonal Antibody dosed every 2 - 4 weeks with 87% reduction in mean attack rate w/ every 2 week dosing 73% reduction every 4 week dose at 6.5 months
What is Takhzyro (Lanadelumab)
Bought a bag, a bracelet, and BMW before Dawnzera launch
What is Heather
In office meal limit for most areas in US
What is $40.00 per person
3 ways to sign up for IONIS EVERY STEP
1. Sign the Dawnzera Patient Enrollment Form and Prescription Form in doctors office
2. Visit DAWNZERA.com/Enroll
3. Call IONIS Every Step
Mean monthly HAE attack rate at week 24 with Dawnzera every 4 weeks
What is 0.44 vs 2.26 for placebo
small molecule, plasma kllikrein inhibitor, oral capsule, dosed daily.
What is Orladeyo (berotralstat)
Carries a travel candle to all work meetings
What is Monea
Attendees who must be entered individually in to Concur for HCP meals
What is MD's PAs. NPS,
Eligible patients who are new to DAWNZERA, one time, one dose supply of DAWNZERA at no charge to assess the administration process and evaluate tolerability of DAWNZERA prior to prescription
What is the Free Trial Program (FTP)
Percent Reduction in mean monthly HAE attack rate at 1 year in the open label study across both Dawnzera arms (placebo controlled study & open label extension)
What is 94%
plasma derived C1-INH, inhibits factor XIIa and plasma kallikrien, dosed every 3-4 days, given by subcutaneous injection
Haegarda
most excited to receive IONIS SWAG
off label questions or unsolicited medical inquires
What is a MIRF
3 forms of documentation that may be required for prior authorization
What is Labs C1-INH levels, Serum C4 levels, genetic test (type III) chart notes describing family hx or prior treatments, HAE attacks information, photos of swells,
Top 3 reasons of patients surveyed who switched preferred Dawnzera
What is "it works better to control my HAE", "less time to administer", "less injection site pain or reaction"
plasma derived C1-INH, inhibits factor XIIa and plasma kallikrien given via IV infusion every 3-4 days
What is Cinryze
most likely to call you on a work day drive
Chris
Dawnzera attorney
What is Sara or Michael
next steps after a denial
-Call IONIS Every Step to assist with appeals process
-suggest office to upload denial letter to IONIS Every Step
share DAWNZERAhcp.com to assist with Letter of Necessity template
Suggest provider scheudle "peer to peer" review with insurance company