There are too many movement disorders
This is the cardinal triad of Parkinson's disease.
Tremor, rigidity, bradykinesia
The neurotransmitter most depleted in Parkinson’s disease
Dopamine
This imaging technique is most commonly used to exclude secondary causes of movement disorders
MRI
This environmental exposure is classically associated with parkinsonism in farmers
Pesticides
This drug is considered first-line for Parkinson’s in patients over 65.
Levodopa/carbidopa
True or false: essential tremor usually improves with alcohol consumption.
True
Mutations in this gene cause abnormal CAG repeats in Huntington’s disease
HTT gene
The “pill-rolling” tremor is best seen when?
At rest
MPTP, a contaminant of synthetic opioids, is toxic to these neurons
Dopaminergic neurons of the substantia nigra
In patients under 65, this drug class is often started to delay levodopa initiation.
Dopamine agonists (e.g., pramipexole, ropinirole)
Huntington’s disease is inherited in this genetic pattern.
Autosomal dominant
Name the intracellular inclusion found in Parkinson’s disease neurons
Lewy bodies
What test can distinguish Parkinson’s disease from essential tremor using dopamine transporter imaging?
DaTscan
Excess exposure to this heavy metal can mimic parkinsonism.
Manganese
These drugs are sometimes preferred in younger patients with predominant tremor but avoided in the elderly due to cognitive side effects
Anticholinergics (e.g., benztropine, trihexyphenidyl)
Name one epidemiologic factor that increases risk of Parkinson’s disease associated with golf courses
Pesticide exposure
Dystonia is thought to arise from dysfunction of this brain region
Basal ganglia
Wilson’s disease can be screened using this slit-lamp exam finding.
Kayser-Fleischer rings
What vitamin deficiency can mimic movement disorders?
Vitamin B12 deficiency
In older patients, this adjunct therapy for wearing-off symptoms is used cautiously because of hallucinations and impulse control disorders.
Dopamine agonists
Wilson’s disease often presents in this decade of life.
2nd or 3rd decade
Spinal muscular atrophy is linked to deletions in this gene
SMN1
What cognitive screening test is frequently used for Parkinson’s-related dementia?
MoCA
Chronic exposure to this recreational drug can cause choreiform movements.
Amphetamines
This treatment is reserved for advanced Parkinson’s disease with severe motor fluctuations refractory to medication, and patient age is an important selection factor.
Deep brain stimulation of the subthalamic nucleus or globus pallidus interna