Schizophrenia

Clinical Symptoms

100

What kind of symptoms are hallucinations?

Positive Symptoms

200

Higher baseline positive symptoms have been associated with more ________ and striatal volume loss over time

Hippocampal

300

Long terms negative symptoms have been found to have decreased brain volume in the dorsolateral _____  _____.

Prefrontal cortex

Neurochemistry and Imaging

100

Name 4 dysfunctional neurotransmitters associated with Schizophrenia.

Dopamine, GABA, Serotonin, Glutamate

200

Which pathways are disrupted due to the alteration of brain structure? 

Dopamine pathways

300

Which type of imaging measures white matter in the brain?

DTI (Diffusion Tensor Imaging)

Treatment

100

What are the only effective medications for schizophrenia?

Antipsychotic medications

200

_______ ________ therapy is demonstrated to be useful in improving functioning in patients with schizophrenia.

Cognitive remediation 

300

Dopamine 2 agonist decreases the production of ___________.

Dopamine