ED
Which adverse effect is unique to tadalafil?
Optic neuropathy (NAION)
If a PDE-5 inhibitor is ineffective, the next step is to
Switch to prostaglandin E₁
Most common malignancy in men in the U.S.
Prostate cancer
Give the PSA levels and what they mean
Normal PSA: < 4 ng/mL (no prostate cancer)
Borderline PSA: 4–10 ng/mL (could be prostatitis or BPH)
High PSA: > 10 ng/mL (likely prostate cancer)
Inflammation of the prostate gland due to infection
Prostatitis
PDE-5 inhibitors should never be used with
Nitrates
In a patient who refuses injections or oral tablets, which option is best?
Staxyn®
Primary androgen driving prostate tumor growth:
DHT
These are used in combination with ADT to block androgen receptor activation.
Anti-androgens
The most common causative organism in prostatitis is:
E. coli
The mechanism of prostaglandin E₁ (alprostadil) involves
B. Increasing cAMP → smooth muscle relaxation
Striant® is indicated for
Testosterone replacement therapy
Gleason score indicates:
Likelihood to spread/aggressiveness
What are the 2 GnRH Antagonist?
Degarelix (Fermagon)
Relugolix (Orgovyx)
A decreased concentration of which element contributes to susceptibility to infection?
Zinc
Testosterone therapy is indicated only when
Testosterone <350 ng/dL and symptoms present
Which PDE-5 inhibitor has the quickest onset
Avanafil
Recommend screening routinely at what ages for Prostate Cancer?
50 and older
LHRH (GnRH) Agonists
Which antibiotic achieves good prostatic penetration?
Ciprofloxacin
Combination therapy is most commonly
Counseling + PDE-5 inhibitor
Which of the following best differentiates prostaglandin E₁ from PDE-5 inhibitors
Independent of nitric oxide
What are the 3 different Androgen Deprivation Therapy?
LHRH agonists
GnRH antagonists
Anti-androgens
Which LHRH (GnRH) Agonist is the only one NOT FDA approved for Prostate Cancer?
Leuprolide (Lupron)
Duration of antibiotic therapy for acute prostatitis is?
10-14 days