BASICS OF ANTIVALS
VIRUS AND MORE
MIX OF EVERYTHING
100

This term describes medicines used to treat viral infections.

What are antiviral drugs?

100

When a virus no longer responds to antiviral treatment.

what is drug resistance

100

After entry, the virus must release its nucleic acid in a process called this

what is uncaring

200

LIST THREE (3) MAJOR CLASSIFICATION OF ANTIVIRALS.

What are:

  • Nucleoside/Nucleotide Analogues
  • Reverse Transcriptase Inhibitors
  • Protease Inhibitors
  • Integrase Inhibitors
  • Entry/Attachment Inhibitors
  • Neuraminidase (Release) Inhibitors
  • Polymerase Inhibitors
  • Interferons (Immunomodulators)
  • Maturation Inhibitors (New)
200

This is the genetic material viruses can be made of.

What is DNA or RNA.

200

HIV primarily infects this type of immune cell.

What are CD4 T-cells?

300

These drugs prevent cleavage of viral proteins into functional units.

What are protease inhibitors?

300

These inhibitors prevent new virus particles from leaving infected cells.

What are neuraminidase inhibitors?

300

Steps in the Viral Replication Cycle

  • Attachment (Adsorption)

    • Virus binds to specific receptors on the host cell surface.

  • Penetration (Entry)

    • Virus enters the host cell by fusion or endocytosis.

  • Uncoating

    • Viral capsid breaks down; viral genome is released into the host cell.

  • Replication (Genome Synthesis)

    • Viral DNA/RNA is copied using host or viral enzymes.

  • Transcription & Translation (Protein Synthesis)

    • Viral proteins (structural and enzymatic) are produced.

  • Assembly (Maturation)

    • Newly synthesized genomes and proteins assemble into new virions.

  • Release

    • New viruses exit the host cell (budding or cell lysis) and infect new cells.

400

HIV uses this enzyme during replication to insert viral DNA into host DNA.

 What is integrase?

400

This happens when viruses undergo mutations that reduce drug effectiveness.

 What is antiviral resistance?

400

This barrier limits how well certain antivirals reach the brain.

 What is the blood–brain barrier?

500

ASK THE PERSON BESIDE YOU SOMETHING  THAT THEY HAVE LEARNT

WHAT IS....

500

Did you learn something new ?

what is yes

500

example of a drug used to treat herpes simplex virus

 Acyclovir

  • Valacyclovir (a prodrug of acyclovir, better oral absorption)

  • Famciclovir