Page 1 (text and #1)
Page 2 (#2 and #3)
Page 3-4 (#4 and #5)
Page 5 (#6)
Page 6 (#7)
100

What are the nucleotides in DNA?

The bases (A, C, G, and T)

100

#2 says examine image 1 and tables 1 and 2. Which page are those resources on?

The image and tables are on page 1

100
#4 is multiple choice. If you look at column A, which 2 answer choice(s) can you rule out based on the information on page 1?

You can rule out row 3 and 4 because p.1 tells you that the mutation is from GAG to GTG.

100

As you go top to bottom in the chart on page 5, does solubility increase or decrease?

The solubility numbers increase as you move down the chart

100

The revisions you select should relate to the effects of something. What are you explaining the results of?

The explanation is about the results of a change in DNA

300

Do you need to know anything about sickle cell disease to answer #1?

No, you need to know about DNA and proteins in general.

300

Which DNA codon is different between the typical and the sickle-cell DNA sequence?

A. Codon 1

B. Codon 5

C. Codon 6

D. Codons 7 and 8

Codon 6 (counting from left to right)

300

According to p. 4, what is the oxygen-carrying capacity of sickle-cell red blood cells under "low oxygen levels?"

60%

300
As you go top to bottom in the chart on page 5, which rows describe hemoglobin that clumps (sticks together)?

The bottom rows describe hemoglobin with high percentages of clumping

300

If the amino acids in a protein change, what might happen to the protein?

The shape of the protein might change. A different protein shape would cause the protein to behave differently

500

How do ribosomes "know" how to make proteins?

Each amino acid added to the protein is determined by 3 mRNA bases, which were made using DNA as a template.

500

#3 asks you to write about the cause AND effects of what?

The cause of the structural change of the protein and the effect on the red blood cells

500

What does the text say is the function of red blood cells?

The function (job) of red blood cells is to carry oxygen

500

Is normal hemoglobin or hemoglobin that is the result of a mutation more likely to clump together?

The sickle-cell mutation causes hemoglobin to have a shape that sticks together easily.
500
Question 7 tells you that the revisions need to be about the 2 effects of a DNA mutation. What are the two effects?

The hemoglobin protein structure changes and the ability of red blood cells to transport oxygen changes.