Dr. James L. LaBelle, MD PhD
BCL-2 Family of proteins are regulators of the intrinsic pathway of apoptosis
How well do you know your lab members?
How well do you know your lab members? (cont.)
Immunology 101
100

In 1990-1994, what undergraduate university did Dr. James L. LaBelle, MD PhD attend?

Lawrence University 

100

What are the two pore-forming pro-apoptotic proteins in the BCL-2 family?

BAK and BAX

100

Alexis Truta performed as the prima ballerina of what famous ballet?

Sleeping Beauty

100

What is Zachary Yasinov favorite swimming stroke?

Sprint freestyle

100

B cells and T cells are a part of the _____ immune system.

Adaptive

200

What is James' middle name?

Lawrence

200

What three anti-apoptotic proteins does BH3 mimetic Navitoclax directly target and inhibit?

BCL-2, BCL-XL, BCL-W

200

What is Elaine Lee and Trang Nguyen's star sign?

Virgo

200

What country does Dr. Nada Aboelella's older brother and his family live?

New Zealand --> Australia

200

Name at least two types of antigen presenting cells.

Dendritic cells, macrophages, and B cells

300

How many followers does James have on X (formally known as Twitter)?

367 followers
300

Which is NOT considered a BH3-only protein?

A. BAD

B. MS1

C. HRK

D. NOXA

E. BIM

B. MS1

300

What color belt is Jocelyn Hsu in Taekwondo?

Red with black stripe

300

How many Pokemon cards has Trang collected on Pokemon Trading Card Game Pocket mobile game? 

4,485 cards

300

Which MHC class is recognized by helper T cells (CD4+)?

MHC class II

400

"The Influence of Ethylene and Spermine on Phosphatase Activity During Senescence in Marchantia polymorpha" is the title of James' first publication as first author. What is the name of the journal and year it was published?

International Journal of Plant Sciences (1997)

400

What is the name of the researcher at the University of Chicago that is famous for discovering BCL-XL?

Craig Thompson

400

Ed Jiang owns a very cute cat. What is it's name?

Puff

400

Which lab member graduated from the same university as the birthplace of Gatorade?

Dr. Rebecca Abraham

400

True or False: During normal secondary immune response, more IgM antibodies are produced than IgG antibody.

False. While IgM antibodies are the first to be produced in a primary response, memory B cells generated during the primary response produce more IgG antibodies during secondary antigen exposure.

500

What was James nickname that was given to him during his cross-country trucking trip adventure as a child?

French Fry

500

According to James, which is correct?

A) BCLxL

B) Bcl-xl

C) BCL-XL

D) BCL-XL

E) Bcl-xL

D) BCL-XL

500

How much can Ryan Park bench?

155 kg/342 lbs (similar weight to one male lion or full size refrigerator)

500

Dr. Huu Van Le obtained his PhD in Chemistry at the Université de Rouen in 2022. His PhD thesis focused on nanogels based on polyelectrolyte complexes from functionalized hyaluronic acid for drug encapsulation and controlled release. What is the name of his advisor?

Prof. Dr. Didier Le Cerf

500

Th17 cells are most crucial for defense against which type of organism?

A) Parasitic helminths
B) Intracellular bacteria
C) Extracellular fungi
D) Viruses

C) Extracellular fungi

Th17 cells are primarily involved in the defense against extracellular bacteria and fungi.