Its in my blood
List the two treatments for hereditary spherocytosis
Folate supplementation, and splenectomy if indicated will not remove spherocytes.
Firstline antibiotic for Treponema pallidum
Penicillin
What is the primary transmission method of monkey pox?
Skin-to-skin
Erythema Nigrans is diagnostic for this disease
What disease is serum detection of (1,3)-B-D-glucan specific for?
Trick question, none, it's a broad spectrum check for invasive fungal infection. It can also be inflated due to antibiotics
Teardrop poikilocytosis and giant platelet forms are hallmarks of this disease
Primary Myelofibrosis
Most deaths from influenza patients are due to
Bacterial Pneumonia
This form of HSV is more likely to cause encephalitis
HSV-1 Encephalitis also causes bell's palsy
HSV-2 Meningitis (also more likely to have asymptomatic shedding of virus)
Upon fundoscopic examination of a patient, you notice a "pizza pie" pattern, this is characterized by what disease
"pizza pie" retinopathy is found in CMV
JAK2 mutation is linked to what disease
Involved in RBC production, linked to polycythemia vera
When is iron chelation indicated in myelodysplastic neoplasms
Patients with multiple tranfusions may need iron chelation
What is the cause of Katayama Syndrome
Acute Schistomiasis
Katayama Syndrome is characterized by acute onset of fever, headache, myalgia, cough, diarrhea(possibly bloody), hepatosplenomegaly, and pulmonary infiltrates.
Daily Double
The discovery of Kaposi’s sarcoma in a 45-year-old patient points to this diagnosis
A patient under the age of 60 with kaposi's sarcoma is diagnostic for AIDS. HHV-8 is also an acceptable answer.
Pneumocystis pneumonia, TB, recurrent pneumonia, candidiasis of trachea / bronchi / lungs, HSV
bronchitis / pneumonitis
• GI: Esophageal candidiasis or HSV esophagitis / gastritis
• Neuro: CNS lymphoma, toxoplasmosis, cryptococcus, PML
Transient upper lid edema in EBV
Hoagland Sign, along with splenomegly, and posterior cervical lymphnopathy are sx of EBV
The Rai Classification system is used to refer to the stages of this blood disease
CLL
This lymphoma is characterized by a translocation between chromosomes 8 and 14, leading to c-myc overexpression.
Burkitt Lymphoma, a non-hodgkins lymphoma.
Follicular lymphoma is the other type of note, it is 14/18 and overproduced bcl-2 overexpression, creating immortal b cells that evade apoptosis.
Most common nonbacterial cause of dysentary
Bacterial Dysentary is typically caused by E Coli. or Shigella
Amoebiasis is the most common cause of non bacterial dysentary.
A patient on metformin is more susceptible to what kind of anemia
B12 deficiency
A patient presents with thrombocyte counts above 1,000,000/mcl and is negative for bcr/abl fusion(philadelphia) gene. What is the first line treatment
Hydroxyurea is the first line treatment for essential thrombocytosis
It is also a first line treatment for sickle cell by increasing fetal hemoglobin
Define the role of haptoglobin in the body
Binds and clears free hemoglobin. Decreased haptoglobin is indicative of hemolysis
In what two scenarios we discussed would you give a tyrosine inhibitor for a patient with hematologic malignancies?
CML
ALL first line treatment is chemo, Tyrosine Kinase is added only if the patient has the Philadelphia chromosome
The mainstay diagnostic of Malaria
Giemsa-Stained blood smear
A female patient who is sexually active complains of dysuria, vaginal discomfort, and a yellow/green discharge. What is the treatment for the most likely cause?
For trichomoniasis, tmt is metronidazole 500 mg bid for 7 days
Single 2g dose in men. All patients should be treated even if asymptomatic.
A patient comes in with condylomata lata. What disease and stage of the disease is this?
Primary Syphillis-Chancre
Secondary-skin and mucous membranes
Acute Chest Syndrome is a characteristic of this disease
In sickle cell anemia, a chest X-ray may reveal lung infiltration. This along with chest pain, hypoxemia, is referred to acute chest syndrome.