Positive marker in infantile hemangioma
GLUT-1 positive
MOA of TXA
Inhibits conversion of plasminogen to plasmin
What type of gland is affected in HS?
Apocrine
Margins for BCC
0.5cm
Blood supply to parascapular flap
Circumflex scapular
What syndrome is comprised of hemangioendotheliomas + thrombocytopenia? Treatment?
Kasabach Merritt, vincristine
MOA of TPA/alteplase
Promotes conversion of plasminogen to plasmin
In tissue expansion, which layer of the skin thickens? Which layer thins?
Thickened epidermis, thinned dermis
What are the necessary margins for the following melanoma depths? In-situ, up to 1mm, 1-2mm, >2mm
0.5cm, 1cm, 1-2cm, 2cm
Blood supply to trapezius flap
Transverse cervical
Mullerian agenesis/ Mayer-Rokitansky-Kuster-Hauser syndrome most associated with what type of organ system defects
Renal defects
MOA of anastrozole and does it need to be stopped perioperatively?
Aromatase inhibitor; no
Main mechanism behind smoking leading to increased wound healing complications
Decreased nitric oxide -> vasoconstriction
% transformation of actinic keratosis to SCC
10%
What muscle does the PAP flap perforator travel through?
Adductor magnus
Underlying mutation in xeroderma pigmentosum
Nucleotide excision repair
Medication to slow progression of Parry-Rhomberg
Methotrexate
Keloids have an ___(increased/decreased) ratio of type I to type III collagen
Increased
Most likely malignant transformation in sebaceous nevus
BCC
Type of local/advancement/rotational flap requiring the least amount of undermining
Keystone flap
Name the mechanism behind poor wound healing in menke
Defective copper transport
What is he MOA of trentinoin and what specific layer of the skin does tretinoin cause thinning of?
MOA = inhibits AP-1 transcription factor
Stratum corneum of epidermis
Skin appendage/structure responsible for re-epithelization in STSG
Sweat glands
Marker that is + in merkel cell carcinoma
+cytokeratin-20
Recipient nerve for functional sensory recovery flap reconstruction of ventral glossectomy and floor-of-the-mouth defects
Lingual nerve