Drug Mechanism
Haloperidol
D2 Antagonist
Citalopram (name 2)
Sexual dysfunction, GI, prolonged QT interval, dry mouth, insomnia
Sertraline (name 2)
Anxiety and Depression
Barbituates
Increase duration of GABA-A channel opening
Chlorpromazine (name 2)
Sedation, orthostatic hypotension, antimuscarinic, increased QT, sexual dysfunction, weight gain
Paroxetine
SSRI
Lithium (name 2)
Renal failure, hypothermia, GI, tremor, ataxia, weight gain
Lithium
Bipolar Disorder
Suvorexant
Orexin antagonist
Ziprasidone
Alprazolam *Bonus 100 if you know half-life (short, int, long)*
Increases the frequency of GABA A channel opening and has intermediate half-life
Clozapine (name 2)
Agranulocytosis, neutropenia, metabolic syndrome, sedation, anti-muscarinic, cardiomyopathy, seizures
Lorazepam (name 2)
Anxiety (acute), seizures, insomnia, muscle spasticity
Duloxetine
SNRI
Quetiapine (name 2)
Weight gain, antimuscarinic, prolonged QT, abuse with cocaine
Flumazenil
BZD antagonist
Desipramine (name 3)
Normal dose: Anti cholinergic, anti alpha rec, antihistamine
Toxic dose: Arrhythmias, EPS, seizures, suicide, liver failure
Pitolisant
Narcolepsy
Risperidone
Antagonist at 5-HT2 and D2 receptors
Risperidone (name 2)
Weight gain, increased prolactin, sexual dysfunction, EPS with high dose
Selegiline (Need low and high doses)
Low dose -> MAO-B
High dose -> MAO-A and MAO-B
Venlafaxine (name 2)
Dry mouth, GI, sexual dysfunction, insomnia
Olazepine
Schizophrenia, Tourette's
Nortriptyline
TCA (blocks reuptake of like everything)
Trifluoperazine (name 3)
EPS, sexual dysfunction, weight gain, TDK, prolonged QT, increased prolactin
Bupropion
DAT and NET inhibitor, may be anti-nicotinic
Zolpidem
Complex sleep behavior
Mirtazepine
Depression
Vortioxetine
Block SERT, agonist and antagonist at different 5-HT receptors
Tranylcypromine (name 3)
Anxiety, hypotension, dry mouth, weight gain, tyramine interaction
Buspirone
Partial agonist at 5-HT1A and antagonist at D2
Flumazenil
Seizures
Fluphenazine
Schizophrenia, Tourette's Chorea
Lithium
Decrease PIP2
Bupropion (name 3)
Sedation, increased appetite, weight gain, increased QT and HR in OD
Trazodone
5-HT reuptake inhibitor, 5-HT antagonist, alpha receptor antagonist, antihistamine
St. John's Wort (name 2)
CYP inhibition, rash, hypomania, photophobia
Tasimelton
Insomnia in totally blind patients with non 24 hour sleep cycle
Quetiapine
Antagonist at 5-HT2, D2, and alpha adrenergic receptors
Esketamine (name 3)
Sedation, GI, hypertension, monitor for 2 hours, misuse