Pharm 1

Asthma & COPD

100

This drug class stimulates β₂ receptors, ↓ intracellular Ca²⁺, and relaxes bronchial smooth muscle. 

Name some examples 

β₂ agonists

Short acting -> Albuterol, Levalbuterol 

Long acting -> Formoterol, Aformoterol, Salmeterol 

Ultra Long acting -> Olodaterol, Vilanterol 

200

This SAMA blocks M3 receptors and lasts about 4–5 hours.

Ipatropium bromide 

300

This PDE-4 inhibitor can cause diarrhea, weight loss, anxiety, insomnia, and depression.

Roflumilast 

400

This biologic targets IL-5Rα, causing eosinophil depletion.

Benralizumab 

500

Name the biologic that targets IgE and the biologic that targets IL-4Rα.

Omalizumab = IgE 

Dupilumab = IL-4Rα

Cough

100

This peripheral antitussive anesthetizes airway irritant receptors.

Benzonatate 

200

This non-opioid central antitussive stimulates sigma-1 receptors and blocks NMDA receptors.

Dextromethorphan 

**Robitussin --> typically first line

300

These opioid antitussives activate μ receptors, ↑ K⁺ efflux, and hyperpolarize neurons in the cough center.

Codeine & Morphine 

400

This mucolytic breaks disulfide bonds in mucoproteins.

N-acetylcysteine (NAC)

**antidote for acetaminophen toxicity 

500

This recombinant DNase I cleaves extracellular DNA, decreasing mucus viscosity.

Dornase alfa 

**DorNase Alfa 

TB

100

This drug inhibits bacterial RNA polymerase.

Rifamycins 

200

This drug inhibits mycolic acid synthesis and can cause peripheral neuropathy.

Isoniazid 

300

What are the four first line anti-TB drugs 

Rifamycins, Isoniazid, Pyrazinamide, Ethambutol

400

This drug inhibits arabinogalactan synthesis and can cause optic neuritis and red-green color blindness.

Ethambutol

500

What drug is used for MDR-TB by blocking mycobacterial ATP synthase and what are its adverse effects?

Bedaquiline

AEs: QT prolongation, risk of death 

Viral Infections

100

Oseltamivir and zanamivir inhibit this viral enzyme.

Neuraminidase

200

This drug inhibits SARS-CoV-2 RNA polymerase.

Remdesivir 

300

This inhaled antiviral can cause bronchospasm and should be avoided in asthma/COPD.

Zanamivir 

400

This RNA-polymerase inhibitor used for RSV has boxed warnings for hemolytic anemia and teratogenicity.

Ribavirin

500

This monoclonal antibody neutralizes an RSV protein, preventing viral binding and entry into cells.

Palivizumab

PAH & Misc

100

These two CCBs are listed for vasoreactive PAH.

Nifedipine & diltiazem

200

This B2 agonist bronchodilator can cause hypokalemia by increasing K⁺ entry into cells.

Albuterol 

300

These two short-acting vasodilators are listed for PAH vasoreactivity testing.

IV adenosine & inhaled NO

400

This PDE inhibitor has a narrow therapeutic window and can cause seizures and arrhythmias.

Theophylline 

**Asthma & COPD medication 

500

This drug inhibits 5-lipoxygenase, while these two drugs block leukotriene receptors. Name all three

Zileuton 

montelukast & zafirlukast