Potpourri
Dermatology
Hematology
General Internal Medicine
Radiology
200
This transfusion product modification reduces the risk of febrile nonhemolytic transfusion reactions, CMV transmission, and Class I HLA alloantibody formation.
What is leukoreduction?
200
This IBD-associated neutrophilic dermatosis presents as a painful ulcer with violaceous, undermined borders — and notably worsens with surgical debridement (pathergy effect).
What is pyoderma gangrenosum?
200
Hematological diagnosis in asymptomatic young man
What is Thalassemia trait? (accept thalassemia)
200
The USPSTF recommends a one-time screening abdominal ultrasound for aortic aneurysm in men within this age range who have ever smoked.
What is 65 to 75 years?
200
The primary safety concern with gadolinium-based contrast agents in patients with eGFR below 30 mL/min/1.73 m² is this rare but potentially fatal condition
What is nephrogenic systemic fibrosis (NSF)?
400
Per USPSTF and ACOG guidelines, low-dose aspirin should be initiated at this gestational week to reduce the risk of preeclampsia in patients with chronic hypertension or other high-risk factors.
What is 12 weeks?
400
In psoriasis, abrupt withdrawal of systemic glucocorticoids can precipitate this severe complication, characterized by widespread erythema involving more than 90% of the body surface area.
What is erythroderma? (Alt: erythrodermic psoriasis)
400
Hematologic malignancy associated with translocation between chromosomes 15 and 17
What is APML?
400
Inducible clonus, hyperreflexia, agitation, diaphoresis, and hyperthermia appearing within 24 hours of adding a second serotonergic agent define this toxidrome.
What is serotonin syndrome?
400
Calcifications in the spleen and mesenteric lymph nodes on CT in an immunocompromised patient from Illinois
What is Histoplasma capsulatum (histoplasmosis)?
600
This brief cognitive screening tool — taking approximately 3 minutes — consists of a 3-item word recall and a clock-drawing test, with a score below 3 validated for dementia screening in primary care.
What is the Mini-Cog?
600
A young woman with IBD-related weight loss and skip lesions on colonoscopy develops tender, raised, erythematous nodules on the extensor surfaces of her shins. What is this reactive dermatosis?
What is erythema nodosum?
600
Autoimmune hematologic disease associated with type 1 diabetes
What is pernicious anemia?
600
An adult with tinnitus, tachypnea, and a simultaneous respiratory alkalosis plus high anion gap metabolic acidosis has likely ingested this drug in toxic quantities.
What is salicylate (aspirin)?
600
This CT finding is classically described in invasive pulmonary aspergillosis in neutropenic patients.
What is the halo sign?
800
Hypereosinophilic syndrome requires an absolute eosinophil count above this threshold on two CBCs more than one month apart, combined with evidence of end-organ damage and no identifiable secondary cause.
What is 1,500/µL (1.5 × 10⁹/L)?
800
Violaceous, flat-topped papules on the wrists and ankles plus Wickham striae are pathognomonic for this dermatologic condition — treated first-line with topical corticosteroids.
What is lichen planus?
800
Eponymous syndrome for development of aggressive large-cell lymphoma in chronic lymphocytic leukemia or small lymphocytic lymphoma
What is Richter transformation?
800
This validated index uses six factors — high-risk surgery, ischemic heart disease, heart failure, cerebrovascular disease, insulin-dependent diabetes, and creatinine >2 mg/dL — to estimate perioperative cardiac risk.
What is the Revised Cardiac Risk Index (RCRI)? (Alt: Lee index)
800
Type of pancreatitis indicated by this CT scan
What is autoimmune pancreatitis?
1000
This eponymous syndrome — severe recurrent hypertensive emergencies and flash pulmonary edema driven by renin-angiotensin activation from critical bilateral renal artery stenosis — is treated with revascularization.
What is Pickering syndrome?
1000
In a patient with persistent central facial erythema, telangiectasias, and inflammatory papules without comedones that flare with sun and spicy foods, this is the first-line topical agent targeting the inflammatory component.
What is topical metronidazole?
1000
Eponym for Coombs-positive warm autoimmune hemolytic anemia and immune thrombocytopenia
What is Evans syndrome?
1000
Fever, diffuse rash, eosinophilia, and internal organ involvement appearing 2–8 weeks after starting allopurinol or an aromatic anticonvulsant define this severe drug reaction.
What is DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms)?
1000
Characterized by right-sided abdominal pain and a distended gallbladder outside its normal gallbladder fossa, with swirling of the cystic artery and duct.
What is gallbladder volvulus?