Building Blocks
Double Helix
Purines & Pyrimidines
Classic Experiments
DNA vs RNA
100

The three components of every nucleotide

What are a phosphate group, a pentose sugar, and a nitrogenous base?

100

The shape Watson and Crick described DNA's structure as

What is a double helix?

100

The two purine bases

What are adenine and guanine?

100

The scientist whose rule states %A = %T and %G = %C in DNA

Who is Chargaff?

100

The base found in RNA but not DNA

What is uracil?

200

The sugar found in DNA

What is deoxyribose?

200

The number of hydrogen bonds between an A–T pair

What is two?

200

The pyrimidine bases found in DNA

What are cytosine and thymine?

200

What Chargaff's rules hinted at, years before the double helix structure was known

What is complementary base pairing?

200

Whether RNA is typically single- or double-stranded

What is single-stranded?

300

The bond that links the sugar of one nucleotide to the phosphate of the next

What is a phosphodiester bond?

300

The number of hydrogen bonds between a G–C pair

What is three?

300

The number of rings in a purine's structure

What is two (a fused six- and five-membered ring)?

300

The organism Hershey and Chase used in their experiment

What is a bacteriophage?

300

The sugar found in RNA

What is ribose?

400

The carbon on the sugar to which the nitrogenous base attaches

The carbon on the sugar to which the nitrogenous base attaches

400

The term for DNA's two strands running in opposite directions (5′→3′ and 3′→5′)

What is antiparallel?

400

The number of rings in a pyrimidine's structure

What is one (a six-membered ring)?

400

The lab tool used to physically separate phage coats from bacterial cells

What is a blender (followed by a centrifuge)?

400

The main job of RNA, compared to DNA's role of storing genetic information

What is building proteins (translating genetic information)?

500

The repeating sugar-phosphate structure that forms the "sides" of a nucleic acid strand

What is the backbone?

500

Why a G–C-rich region of DNA has a higher melting point than an A–T-rich region

What is because it has more hydrogen bonds holding the strands together?

500

Why a purine always pairs with a pyrimidine, never purine-purine or pyrimidine-pyrimidine

What is because it keeps the double helix's width constant?

500

What the Hershey-Chase experiment proved

What is that DNA, not protein, is the genetic material?

500

The structural reason DNA is more chemically stable than RNA

What is the absence of a hydroxyl (OH) group on the 2′ carbon of deoxyribose?