Drugs
AV nodal blocker which should be avoided in amyloid heart-
Digoxin
Diastolic mitral sound characteristic of Mitral valvulitis in Rheumatic fever-
Carey Coombs murmur
Wooly hair, keratoderma of palms and soles with cardiomyopathy
-Naxos disease
In patients with cardiogenic shock, emergency revascularization did not significantly reduce overall mortality at 30 days. However after 6 months there was a significant survival benefit. LA revised should be strongly considered for patients with acute MI complicated by cardiogenic shock
SHOCK trial
Nobel Prize winner in 1985 for the discovery of LDL-cholesterol receptors
Michael Brown and Joseph Goldstein
Hyperthyroidism can be worsened by Iodine content of Amiodarone due to what effect -
Jod-Basedow effect
Congenital pulmonary stenosis with cafe-au-alit spots-
Watson's syndrome
Progressively increasing PR interval, grouped beating -
Wenckebach
Cangrelor significantly reduces the risk of ischemic events including stent thrombosis during PCI with no significant increase in bleeding
Champion Phoenix trial
Who invented the first internal cardioverter-defibrillator
Michel Mirowski
Dose of warfarin which is relatively safer in pregnancy
Less than or equal to 5mg/day
Syndrome of Mitral stenosis and Atrial septal defect-
Lutembacher
A myocardial infarction-associated pericarditis, usually occurring one week after the onset of infarction, but may occur several months afterwards
Dressler syndrome
First large RCT showing TAVR superiority in low‑risk patients, expanding TAVR’s indication beyond high/intermediate risk.
Partner 3 trial
In 1628 a famous publication - ‘De Motu Cordis’ described heart and its circulatory function for the first time, who was the author?
William Harvey
Statin metabolized by CYP3A4 -
Simvastatin, Atorvastatin, Lovastatin
Indication for Pulmonary stenosis balloon valvulotomy
-Symptomatic
Mean gradient >30/Peak gradient > 50mmHg.
-Asymptomatic
Mean gradient >40/Peak gradient >60mm Hg, in association with less than moderate PR
A clinical triad of early contractures of the elbow, Achilles tendon, and posterior cervical muscles, progressive skeletal myopathy, and cardiac manifestations. These include sinus bradycardia, atrial fibrillation and atrial flutter initially, progressing to higher levels of AV block, sustained ventricular tachycardia and ventricular fibrillation.
Emery-Dreifuss muscular dystrophy
The trial that shows the use of Betablockers has no benefits for perioperative outcomes
POISE trial
First coronary balloon angioplasty was done by?
Andreas Gruentzig
Age and weight cut off [relative contra-indication] for Prasugrel
Age > 75yr, Wt. < 60kg
Dabigatran is not appropriate as an alternate to warfarin for prevention of thromboembolic complications in patients who require anticoagulation after the implantation of a prosthetic heart valve. The use of dabigatran was associated with increased rates of thromboembolism and bleeding complications, thus showing no benefit and an excess risk
RE-ALIGN TRIAL
Sudden collapse of the cervical veins that were previously distended at each diastole, caused by an adherent pericardium.
Friedreich’s disease
Also known as mediastinopericarditis adhesiva, or Friedreich’s sign.
In patients at high risk of cardiovascular events but without diabetes, targeting systolic blood pressure of less than 120 mmHg as compared with less than 140 mmHg resulted in low heart rates of 50 nonfatal Mace and death from any cause of those significantly higher rates of adverse effects
SPRINT trial
The American Heart Association was founded, establishing a formal professional society for the field in
1924