Endocrinology
GI
Cardiovascular
Dermatology
History of Medicine
100

Common cause of hypothyroidism, associated with anti–thyroid peroxidase antibodies

Hashimoto disease

100

 Form of colitis associated with NSAID use

 Microscopic colitis

100

 Most common type of primary cardiac tumor in adults

Atrial myxoma

100

Diagnostic gold standard test for allergic contact dermatitis

Patch test

100

Nursing namesake for the palpable umbilical nodule indicative of metastatic cancer

Sister Mary Joseph (accept Julia Dempsey or Dempsey)

200

Preferred class of oral diabetes medication in patients with type 2 DM and heart failure

SGLT2 inhibitors

200

 Virus associated with porphyria cutanea tarda, mixed cryoglobulinemia, membranoproliferative glomerulonephritis and non-Hodgkin's lymphoma

Hepatitis C virus

200

Inherited CV disease whose features include asymmetrical LV septal thickness and myocardial fibrosis

Hypertrophic cardiomyopathy (HCM); also accept Hypertrophic obstructive cardiomyopathy (HOCM)

200

Skin condition associated with the 'oil-drop' sign of the nail, nail bed hyperkeratosis, and nail crumbling

Psoriasis 
200

Creator of the smallpox vaccine

Edward Jenner

300

Most common manifestation of primary aldosteronism

Hypertension

300

Condition causing recurrent dysphagia with rings and furrows with luminal narrowing on EGD

Eosinophilic esophagitis

300

FDA-approved SGLT2 inhibitor that reduces cardiovascular death and hospitalization for heart failure in adults with heart failure, irrespective of ejection fraction

Empagliflozin

300

 The appearance of new psoriatic lesions after mechanical irritation

Koebner Phenomenon

300

1990 Nobel laureate who performed the first human kidney transplantation in the U.S.

Joseph Edward Murray

400

Chronic hyponatremia with serum sodium 124 mmol/L, serum osmolality 265 mOsm/kg, urine osmolality 520 mOsm/kg, and urine sodium 48 mmol/L, with normal thyroid and cortisol. What is the most likely mechanism?

Inappropriate ADH secretion causing impaired free water excretion

400

Angiotensin receptor blocker associated with celiac-like enteropathy

Olmesartan

400

Used to treat breast cancer, class of chemotherapy drug associated with cardiomyopathy

Anthracycline

400

Triad of dermatitis, asthma, allergic rhinitis

Atopic dermatitis

400

 Victorian-era toy creating sound akin to pulses felt in aortic regurgitation

Water Hammer

500

Hypercalcemia, low-normal parathyroid hormone, suppressed parathyroid hormone-related peptide, and elevated 1,25-dihydroxyvitamin D. Chest CT shows diffuse mediastinal and hilar lymphadenopathy. Which mechanism best explains his hypercalcemia?

1 alpha-hydroxylase activity in granulomatous tissue (Sarcoidosis)

500

Most common gene mutation associated with hereditary pancreatitis

PRSS1 (cationic trypsinogen)

500

P2Y12 antagonist with dyspnea as a side effect

Ticagrelor

500

Photosensitive eruption strongly associated with a positive anti-Ro/SSA antibody

Subacute cutaneous lupus erythematosus

500

Class of oncologic medication whose discovery earned Professor James Allison the Nobel Prize in Physiology or Medicine in 2018

Immune Checkpoint Inhibitors