Primary Care
Cardiology
GI
Rheumatology
Oncology
100

In a patient with type 2 diabetes and established ASCVD, these are the two medication classes preferred independent of baseline A1c or metformin use because of proven cardiovascular benefit.

What are GLP-1 receptor agonists and SGLT2 inhibitors?

100

When treating heart failure, ensuring patients are on the best medications at optimal doses is referred to by this four-letter abbreviation.

What is GDMT?

100

Before initiation of any anti-TNF biologic, this latent infection is screened and treated for if necessary.  

What is TB?

100

This crystal arthropathy is caused by deposition of monosodium urate crystals.

What is gout?

100

Patients receiving this chemotherapy agent may notice red/orange discoloration of their urine after treatment, often alarming patients but is clinically harmless.

What is Doxorubicin?

200

This lipid-lowering medication is recommended in very high-risk ASCVD patients when LDL remains at or above 70 mg/dL despite maximally tolerated statin therapy and ezetimibe.

What is a PCSK9 inhibitor?

200

In its 2.5 mg dose, this medication, which inhibits vitamin K epoxide reductase, is typically presented in this color.

What is green?

200

Chronic use of PPIs, especially in elderly patients, can put them at increased risk for deficiencies in magnesium and this vitamin essential for nerve function.

What is Vitamin B12?

200

This adverse effect is classically associated with long-term hydroxychloroquine use and requires baseline and ongoing ophthalmologic monitoring.

What is retinopathy?

200

This imaging modality is most commonly used to monitor LVEF in patients receiving cardiotoxic chemotherapy such as anthracyclines.

What is an echocardiogram?

300

In a patient with resistant hypertension on an ACE inhibitor or ARB, calcium channel blocker, and thiazide-like diuretic, this medication is the preferred fourth-line agent based on data from the PATHWAY-2 trial.

What is spironolactone?

300

This class 2 antiarrhythmic agent may mask hypoglycemic symptoms. 

What is sotalol?

300

Both direct acting antiviral agents, Harvoni® and Epclusa®, have this NS5B inhibitor in common.

What is sofosbuvir?

300

This oral targeted synthetic DMARD class carries boxed warnings for MACE, malignancy, thrombosis, and serious infection.

What are JAK inhibitors?

300

NSAIDs are typically first-line for bone pain associated with filgrastim or pegfilgrastim, but this medication is commonly used off-label when pain persists.

What is loratadine (Claritin)?

400

This antihypertensive class is associated with dose-related pedal edema due to preferential arteriolar dilation.

What are dihydropyridine calcium channel blockers?

400

The new updated VMFH enoxaparin guidelines from January 2026 states this weight is the new cutoff low body weight for patients. 

What is 50 kg?

400

This anti-inflammatory class of medication can often be beneficial for ulcerative colitis or ankylosing spondylitis, but may come at the risk of acne.  

What are JAK inhibitors?

400

This biologic for osteoporosis is a RANKL inhibitor that decreases osteoclast activity.

What is denosumab?

400

Patients should ideally receive all vaccines this many weeks before starting chemotherapy for optimal immune response.

What is ≥2 weeks for inactivated, ≥4 weeks for live vaccines?

500

This blood pressure medication can increase lithium concentrations and risk lithium toxicity by reducing renal clearance.

What are thiazide diuretics?

500

Camzyos® for the treatment of obstructive hypertrophic cardiomyopathy (HCM) should be discontinued after LVEF <50% on 2.5 mg QD this many times.

What is two times?

500

A unique 4-letter suffix is attached to core drug names to ensure pharmacovigilance and distinguishment from the reference product. The brand name of this adalimumab (Humira®) biosimilar, with the suffix -bwwd, is _?

What is Hadlima?

500

This monoclonal antibody targets CD20 and is used in RA and ANCA-associated vasculitis.

What is rituximab?

500

When this class of medications is included in a CINV regimen, the dose of dexamethasone is typically reduced due to CYP3A4 inhibition.

What are NK1 receptor antagonists?