DARZALEX
CARVYKTI
TECVAYLI
OLYMPIC
PORTFOLIO GOALS
200

The primary endpoints for the PERSEUS, MAIA and CEPHEUS trials

What is PFS for PERSEUS & MAIA, MRD negativity rate for CEPHEUS?

200

Approximately this number of letters have been sent by MM patients and caregivers to government and healthcare organizations to advocate for the importance of CARVYKTI access in Canada

What is >5600?

200

The number of patients treated worldwide by TECVAYLI

What is >22,000 patients?

200
The 5 colours of the Olympic rings

What are blue, yellow, black, green, and red?

200

The movie this famous line is from (cue Alex)

What is Home Alone?

400

The definition of "not candidates for transplant" for the CEPHEUS indictation.

What is <70 years transplant ineligible, or <70 and refusal to transplant [meaning was not planned as initial therapy], ≥70 years? 

400

CARVYKTI received a LOE from the pCPA on this date 

What is February 6th, 2026? 

400

The key commercial execution step if an HCP is interested in prescribing TECVAYLI and/or TALVEY for the first time

What is the Risk Management Tool rep-triggered e-mail? 

400

The sport making its Olympic debut at the 2026 Winter Games

What is Ski Mountaineering?

400

The two access goals for Talvey in 2026

What are (1) what are positive CDA recommendation with modified criteria (2) Negotiate for Quebec with pCPA in a manner compatible with a subsequent TAL-1 negotiation for ROC

600

The MRD negativity rate for CEPHEUS at the 58.7mo follow-up

What is 60.9% for D-VRd vs 39.4% for VRd?

600

This efficacy outcome is considered the single greatest driver of HCP treatment choice for RRMM

What is associated with an OS benefit? 

600

IWMG Sequencing recommendations for anti-BCMA therapies 

What is CART, then bispecifics, then antibody drug conjugates (ADC or Blenrep)? 

600

The number of Canadian athletes at the 2026 Winter Games (same number as in 2010!)

What is 206?

600
CARVYTKI ATU share target in 2L

What is 30%?

800
Two of the top 4 drivers for HCP preference when choosing between quad-based regimens

What is: (1) route of administration (2) patient preference (3) less frequent dosing schedule (4) familiarity with regimen? 

800

According to both patients and HCPs, this remains the greatest barrier to CAR-T referral in Canada (not access!!)

What is logistical complexity (travel and accommodation)? 

800
Two reasons why a center may be a focus center this cycle

Either (a) does not have a pathway to offer TEC (b) has a pathway that may be limited by capacity in the future (c) has a competitive risk 

800

The Canadian flag bearers at the 2026 Winter Olympic Games

Who are Mikaël Kingsbury and Marielle Thompson,?

800
The 4L new patient share target for TECVAYLI in 2026 
What is 68%?
1000

The reduction in injections between MAIA and IMROZ or CEPHEUS and IMROZ in the first 1 year of treatment? 

What is 5 less injections using MAIA vs IMROZ or 9 less injections using CEPHEUS vs IMROZ? 

1000

The key message we will deliver to HCPs regarding the meaningful OS improvement demonstrated by CARVYKTI in the 33-month follow-up data

What is CARVYKTI, a one-time infusion, is the first and only cell therapy to demonstrate a statistically significant and clinically meaningful improvement in OS vs. the SoC (DPd or PVd) in len-ref MM patients as early as first relapse? 

1000

The overall response rate of TECVAYLI at 29.5 months AND the number of responders who achieved complete response or better

What is 62.4% ORR and 7 in 10 responders achieved CR or better? 

1000

Location of the 2028 Summer and 2030 Winter Olympics

What are Los Angeles and French Alps?

1000

New Patient share target for DARZALEX Front-line newly diagnosed Multiple myeloma

What is >84%?