Ossification
Growth Factors
Bone Cells
Bone Disorders
The Osteon
100

 This type of ossification forms the flat bones of the skull

intramembranous ossification

100

Which vitamin is essential for the absorption of calcium from the small intestine

Vitamin D

100

These cells are responsible for building new bone matrix

osteoblasts

100

This disorder is characterized by soft bones and bowed legs in children

Rickets

100

This is the main structural unit of compact bone.

What is an Osteon?

200

What is the "template" that endochondral ossification uses to form most bones

a hyaline cartilage model

200

Explain how weight-bearing exercise helps to strengthen bones.

Mechanical stress from exercise stimulates osteoblasts to build new bone

200

This type of cell breaks down or resorbs old bone tissue.

Osteoclasts

200

What is a major risk factor for osteoporosis related to diet

A long-term lack of calcium and/or Vitamin D

200

This hollow channel at the center of the osteon contains blood vessels and nerves.

what is the central canal?
300

Describe the process of bone formation for intramembranous ossification

Intramembranous forms bone directly from a fibrous membrane

300

What general role do hormones play in bone growth and remodeling

They regulate the activity of bone-forming and bone-resorbing cells to maintain bone homeostasis

300

This cell is a mature bone cell that maintains the bone matrix.

osteocytes

300

Name at least two factors that make a person more likely to develop osteoporosis

Being post-menopausal, having a small body frame, smoking, or a sedentary lifestyle.

300

These are the rings of bone matrix that surround the central canal.

Concentric lamellae

400

Describe the process of bone formation: endochondral ossification

endochondral replaces a hyaline cartilage model with bone

400

What role does Vitamin C play in bone growth?

Vitamin C is needed to form collagen fibers

400

These cells live in small spaces called lacunae within the bone matrix.

Osteocytes

400

What is rickets primarily caused by?

severe deficianecy of Vit D + calcium

400

These are tiny canals that connect osteocytes to each other and to the central canal, allowing for communication and nutrient exchange.

canaliculi

500

what is the difference between endochondral and intramembranous ossification?

Intramembranous forms bone directly from a fibrous membrane, whereas endochondral replaces a cartilage model with bone

500

How does the growth hormone (GH) promote bone growth?

It stimulates osteoblasts, promotes calcium absorptions in small intesting, stimulates cartilage growth at epiphyseal growth area

500

This is the process of bone formation that osteoblasts perform

Ossification

500

This disorder is characterized by a loss of bone matrix and minerals, making bones porous, brittle, and prone to fractures

osteoporosis

500

This type of lamellae forms the individual rings of an osteon

concentric lamellae