Antibodies and Antigens
Biopharmaceuticals with mab in their naming are what type of biopharmaceutical
Monoclonal antibodies
List the 7 key steps of vaccine manufacturing.
Production
Purification
Inactivation
Formulation
Filling
Batch Release
Packaging and Shipping
What are the main types of vaccines?
Viral and Bacterial
Briefly explain what the difference is between a monoclonal antibody and a polyclonal antibody
•Monoclonal antibodies- bind to a single epitope (area of the antigen recognized by the antibody)
•Polyclonal antibodies- bind to multiple epitopes
After a biopharma company releases a product who performs the secondary release to the market to ensure the safety of the product and what do they do to ensure this?
Regulatory Authorities or Health Authorities
List 7 types of biopharmaceutics
•Vaccines
•Gene therapies
•Whole blood immunosera
•Antigens
•Hormones
•Cytokines
•Cell therapies
•Monoclonal antibodies
Define antigen
Antigens are any molecule, macromolecule virus particle or cell that contains a structure recognized and bound by an immunoglobulin (antibody) or T-cell receptor. Presence of antigens in the human body triggers an immune response.
Briefly explain what a vaccine is and how they work
Vaccines are a preparation (dead or attenuated antigens etc,) administered into the human body through various methods to stimulate the immune system into response.
Define Antibody
Antibodies are protective proteins produced by the immune system in response to the presence of antigens.
Briefly explain what monoclonal antibodies are and how they work
Monoclonal and polyclonal antibodies are laboratory made proteins that mimic the immune system’s ability to fight pathogens and diseases. They can also be used to restore or enhance the immune system. These antibodies are made by cloning white blood cells. All antibodies derived this way can be traced back to a single parent cell.