4D History
4DMT collaborated with this subsidiary of AstraZeneca to develop gene therapies for chronic lung diseases
What is MedImmune?
This scientist won the 2018 Nobel Prize in Chemistry for her pioneering work in directed evolution of enzymes
Who is Frances Arnold?
This cell can divide symmetrically or asymmetrically
What is a stem cell?
The zip code of 4DMT offices
What is 94608?
mRNA and this viral vector are the leading vaccine technologies for COVID-19
What is adenovirus?
Our 4 guiding principles are represented by this symbol in the "4DMT Vision" mural
What is a tree?
This "million dollar drug" was the first approved gene therapy in the EU
What is Glybera?
These 3 nucleotides contain pyrimidines
What are thymine, cytosine, and uracil?
The number of 4DMT conference rooms in 5858 Horton
What is 6?
Pfizer's mRNA vaccine is encapsulated in this type of non-viral vector
What is a lipid nanoparticle (LNP)?
Several leaders at 4DMT were co-founders of this oncolytic cancer vaccine company
Luxturna is approved to treat inherited retinal disorders caused by mutations in this gene
What is RPE65?
The AAVS1 safe harbor site is located on this chromosome in the human genome
What is chromosome 19?
This document outlines the desired characteristics of a product to treat particular diseases
What is a Target Product Profile (TPP)?
The spike protein of SARS-CoV-2 binds to this receptor on human cells
What is ACE2?
In 2015, 4DMT entered a collaboration and license agreement with this gene therapy company for ocular indications
What is AGTC?
Ashanti DeSilva, the very first gene therapy patient, was treated in 1990 for this disease
What are SCID (severe combined immunodeficiency)?
AAV uses this part of its capsid to escape the endosome
What is the phospholipase A2 domain?
The general session of the 2019 holiday offsite was held at this property
Where is the Estate Yountville?
Transmission of SARS-CoV-2 from humans to this farmed animal in Denmark has led to a new mutant strain of the virus
What is a mink?