This SSRI is known to have a black warning box of Suicidality
Fluoxetine
GOLD standard for BPD!
Lithium
Alprazolam's drug class
Benzodiazepine
What is the dosage range for Amitriptyline? What is considered toxic?
120-250 mg/mL is normal
>500 is toxic!
Which electrolyte is known to be replaced by Lithium
Sodium (Na+)
This medication is known to be extremely hard to come off of! Known to cause discontinuation syndrome! You should never stop this medication abruptly. (HINT: Also causes HTN so monitor BP/HR)
Venlafaxine (Effexor)
What is the therapeutic range for Lithium?
0.6 to 1.2 mEq/L
Which Neurotransmitter does Xanax work on??
Binds to specific receptor sites in GABA complex and enhances and amplify action of GABA
This medication is used off label for Bulimia and cannot be taken with chocolate or caffeine
Phenelzine
Grapefruit juice is known to interact with with anti-anxiety medication
Buspirone
This medication is known to have weird food interactions which can lead to a hypertensive crisis due to tyramine
Phenelzine
This anticonvulsant is also used for BPD and it is known to have SE such as SJS, hyperammonemia, hepatotoxicity, PCOS, stomach upset, etc.
Valproic Acid
Buspirone cannot be mixed with this medication if it has been used in the last 2 weeks
MAOI
Fluoxetine (Prozac)
This NDRI is known to have increase BP/HR, N/V, SI, weight loss, etc.
Bupropion
This medication is used off label for sleep! Also known to be veryyyyy cardiotoxic
Amitriptyline
SE of Lithium Toxicity (HINT: LITHIUM)
Leukocytosis, increased tremors, hypothyroidism, increased urine, and fetal abnormalities such as Ebstein's anomaly (Do not give this drug to Moms)
Since Xanax is a Benzodiazepine give at least 3 SE
CNS depression, respiratory depression, anterograde amnesia, tolerance, dependence, toxicity, abuse, etc.
Interventions if patient Overdoses on Amitriptyline
Use gastric lavage, activate charcoal, and use sodium bicarb NAHCO3 (for arrhythmia)
Ibuprofen, ACE inhibitors, and Thiazide diuretics
Known to be contraindicated in patients with eating disorders, cardiac disease, or seizure disorders and causes strange dreams
Bupropion
What nursing interventions are done for Valproic Acid? HINT: What labs do we want to review and which organ do we worry about
VPA levels, LFT, CBC, and assess for s/s of liver dysfunction
Name three SE of Buspirone
Paradoxical reactions (insomnia, anxiety, restlessness), dizziness, nausea
Name the SSRI, SNRI, TCA, and MAOI drugs
Fluoxetine
Venlafaxine
Amitriptyline
Phenelzine
If a patient undergoes a hypertensive crises taking Phenelzine what intervention must be done?
IV Phentolamine or SL Nifedipine- rapidly drops BP