Science/Medical Stuff
History
Movies
Video Games
Books/Literature
100

The element with the atomic number of 1.

What is hydrogen?

100

This is the oldest city in America. 

What is St. Augustine?

100

In 2009 Disney animated movie "Up", this is the location that Carl Fredrickson tries to reach for his wife.

What is Paradise Falls?

100

This is the main character in Grand Theft Auto 4.

Who is Niko Bellic?
100

In the Diary of a Wimpy Kid series, this is Greg Heffley's older brother. 

Who is Rodrick Heffley?

200

The small dangly thing at the back of your throat.

What is the uvula?

200

The man whose name the term "America" derived from.

Who is Amerigo Vespucci?

200

The weapon used to defeat the Killer Rabbit of Caerbannog in "Monty Python and the Holy Grail."

What is the Holy Hand Grenade (of Antioch)?

200

This video game character has the nickname of "The Blue Blur."

Who is Sonic the Hedgehog?

200

This is Juliet's family featured in William Shakespeare's "Romeo and Juliet."

Who are the Capulets?

300

This man discovered the Archimedes principle while taking a bath.

Who is Archimedes?

300

What historical American event happened on December 16. 1773?

What is the Boston Tea Party?

300

This is the hotel that John Wick stayed at that served as neutral grounds and where conducting criminal business is forbidden in the John Wick franchise.

What is the Continental?

300

In the Doom Franchise, this is the pet rabbit of the Doomslayer/Doomguy.

Who is Daisy?

300

In the "Odyssey", he is the divine father of the cyclops Polyphemus.

Who is Poseidon?

400

The freezing point of water in Fahrenheit. 

What is 32oF?

400
The location from which Apollo 13 mission was launched.

What is the Kennedy Space Center?

400

This is the country of origin for the character Borat.

What is the Republic of Kazakhstan? 

400

This game series features a demon hunter whose name alludes to The Divine Comedy.

What is Devil May Cry?

400

The titular character of Victor Hugo's "The Hunchback of Notre-Dame."

Who is Quasimodo?

500

This is the biggest organ of the human body.

What is the skin?

500

This man founded the Standard Oil Company in 1870 and controlled the majority of oil in the US at his peak.

Who is John D. Rockefeller?

500

In Star Wars: Episode IV - A New Hope, this is where Luke Skywalker wanted to go to get some power converters.

What is Tosche Station?

500

This video game company was originally founded as a playing card manufacturer in 1889.

What is Nintendo?

500

In the George Orwell novella "Animal Farm", this is the rules that the animals followed that Napoleon and his pigs later changed as the story progressed.

What are the Seven Commandments of Animalism?