Organelle functions
Functions of mitochondria
Power House of the cell
Singer and Nicolson
Functions of smooth endoplasmic reticulum
Detoxification
Describe the movement of components across lipid bilayer? Which movement is allowed and which movement is restricted?
Lateral movement is allowed and flip flop movement is restricted except under certain conditions
Where are proteins synthesized
Ribosomes (RER)
How cholesterol affects the fluidity of membrane?
At temperature below Tm cholesterol increases fluidity and vice versa
I cell disease is due to the defective function of which organelle?
Lysosomes ( protein targeting defect)
More cis unsaturated fatty acids increase fluidity. Explain
Cis double bonds will create a kink in the hydrocarbon chain and have a marked effect on fluidity . Transfatty acids decreases fluidity due to close packing of hydrocarbon chains
Why lactic acidosis is a feature of mitochondrial disorders?
Reducing equivalents does not enter ETC and Oxidative phosphorylation. Instead reduces pyruvate to lactate.
Why fluidity of plasma membrane should be maintained?
The plasma membrane must maintain its fluidity to allow essential proteins to move and function properly for cell communication and transport