Models
Semiconservative
Elongation
Antiparallel
Proteins + Accuracy
100
What did Watson and Crick realize?
What is DNA's base pairing rule could form as a template to form a copy?
100
Where does the DNA replication begin?
What is the sites called origins of replication?
100
What kind of matter is the replicating done is?
What is orderly?
100
What does anti-parallel mean?
What is one strand is in the 5' to 3' direction and the other side of the double helix is in a 3' to 5' direction?
100
What does primase do?
What is allows the joining of RNA nucleotides to the exposed DNA bases at the point of replication
200
Copying from a template is...
What is semiconservative replication?
200
WHat is the difference of Eukaryotic and Bacterial DNA?
What is E- linear and has thousands of origins B- circlular and has one origin
200
What does primase attach to the replication fork?
What is a primer made of 5-10 bases?
200
What does only being able to replicate in the 5' to 3' direction do?
What is create a leading and lagging strand?
200
WHat does DNA polymerase III do?
What is add DNA nucleotides in the 5' to 3' direction?
300
What are the three models of replicating DNA?
What is semiconservative, conservative, and dispersive?
300
What does helicase do to the DNA?
What is unzipping creating bubbles in multiple parts of the DNA strand?
300
In which way are DNA nucleotides added to the growing strand?
What is 5' to 3'?
300
HOw is the lagging strand created?
What is in fragments, okazaki fragments?
300
WHat is the purpose of DNA polymerase I?
What is removing the primer from the 5' end and replaces it with nucleotides.
400
How did scientists discover DNA was semiconservative?
What is using heavy isotopes of nitrogen and viewing that the first replication created a hybrid of light and heavy and the second replication had two hybrid strands and two completely light strands?
400
what is in the end of each bubble?
What is a replication fork
400
why are 2 phosphates lost during the bonding of deoxynucloside thriphosphates?
What is to provide energy for the bonding of nucleotides?
400
WHy does the lagging strand still need DNA polymerase III, a primer and primase?
What is the components are necessary to create each fragment, the primer and primase is used more then once because it is in fragments?
400
What is DNA ligase?
What is the connecting enzyme for the okazaki fragments of the lagging strand?
500
Who are some important scientists in the discovery of semiconsevative model?
Who is Matthew Meselsohn and Franklin Stahl?
500
HOw do the bubbles enlarge and what does this show
What is both directions, showing the process is bidirectional and will fuse together to create identical daughter DNA molecules>?
500
how many phosphate groups are on a dNTP?
What is 3
500
Why is there a lagging strand?
What is there is a delay in the synthesis of the lagging strand?
500
WHy are multiple replication origins needed in eukaryotic DNA?
What is there are so many nucleotides and it is a faster process if it is done in this form?