Chapters 6 and 7
Adrenergic Bronchodilators mimic the action of ?
epinephrine
You have received an order for 5 mL of a 10% mucomyst concentration. The pharmacy only has 20% mucomyst. How much will you need to draw up for the treatment.
2.5 mL
What should a patient prescribe fluticasone propionate do after administration and why?
rinse out their mouth to prevent thrush.
Trade name for aerosolized pentamidine
Nebupent
The drug used to treat hypoxic respiratory failure in newborns with pulmonary hypertension is?
Inhaled Nitric Oxide (iNO)
An anticholinergic that can be aerosolized is?
Ipratropium bromide
Atrovent
How does dornase alpha work?
Breaks down DNA in sputum
What two generic medications are in Advair HFA?
fluticasone propionate and salmeterol
Clinical indication for Cayston (aztreonam).
Cystic fibrosis patients colonized with pseudomonas
T/F Nitric oxide is a selective pulmonary vasodilator.
True
Because it is rapidly inactivated by hemoglobin, its effects are localized to ventilated lungs, avoiding systemic hypotension.
Alpha receptors, beta1 and beta 2 receptors are stimulated by this catecholamine?
epinephrine
How does N-acetyl cysteine, a mucolytic work making it easier to mobilize sputum?
Breaks the disulfide bonds in mucus proteins, thinning it for easier expulsion.
The primary inflammatory cells seen in COPD are which type?
Neutrophils
Inhaled Pentamidine is indicated for?
Prevention of Pneumocystis jiroveci pneumonia(PJP) or when the oral TMP-SMX is not tolerated.
A common side effect of diuretics is?
hypokalemia
The recommended dosage for continuous nebulization of albuterol.
10-15 mg/hour
What is the trade name for dornase alfa and what is the dosage?
Pulmozyme.
Dosage 2.5 mg/2.5 mL
What class/family of medications is fluticasone propionate?
corticosteroid
Early phase of of asthma reaction time is?
Peaks at 15 mins and declines over the next hour.
IGE mediated cells active mast cells to release inflammatory mediators (histamine, prostaglandins, and leukotrienes).
Name two non-depolarizing NMBAs
Agents include: – Atracurium – Cisatracurium (Nimbex) – Mivacurium • Shortest duration of action – Pancuronium • Longest duration of action – Rocuronium – Vecuronium
From which muscarinic receptors does tiotropium disassociate the slowest.
M1 and M3
What are the theophylline ranges for asthma.
5 to 15 mcg/mL
Name a monoclonal antibody used to control asthma.
omalizumab; Xolair
What type of anti-infective is Relenza?
Anti-viral agent
List two agents used in shock management.
Fluids, norepinephrine, epinephrine, isoproterenol, dopamine, vasopressin,