HCL
Diagnosis
Cell Features
History
Treatment
100

What was hairy cell leukemia originally referred as?

What is leukemic reticuloendotheliosis?

100

What type of blood cell is primarily affected in hairy cell leukemia?

What is B Cell?

100

What test is used to confirm hairy cell leukemia?

What is a bone marrow biopsy?

100

What is the earliest known surgical procedure for cancer?

What is amputation?

100

Can projections like the ones in hairy cells be seen in other cases?

What is yes?

200

What age group does HCL affect?

What is middle-aged or older adults?

200

What is a common symptom of hairy cell leukemia?

What is fatigue?

200

What genetic mutation is commonly found in hairy cell leukemia?

What is BRAF V600E?

200

What is the normal range of white blood cells in a healthy blood sample?

What is 4,500 to 11,000 WCXs per microliter,

200

Who is considered the "father of surgery" and described various types of cancer?

Who is Hippocrates?

300

What is the median age of the HCL pts.

What is 50?

300

What is the primary diagnostic tool used to confirm hairy cell leukemia?

What is bone marrow biopsy?

300

What is a targeted therapy drug used in hairy cell leukemia?

What is vemurafenib? 

300

In what century did radiation therapy begin to be used as a cancer treatment?

What is the late 19th century?

300

What is splenomegaly?

What is an enlarged spleen?

400

What HCL characterized by?

What is pancytopenia, splenomegaly, myelofibrosis, and abnormal mononuclear cells with hair-like projections?

400

What treatment is often used for hairy cell leukemia?

What is chemotherapy? 

400

What is a characteristic marker found on hairy cells?

What is CD103?

400

What is a possible side effect of hairy leukemia treatment?

What is infection?

400

What is pancytopenia?

What is a deficiency of all three blood cell types?

500

Untreated HCL may cause....

What is crowding of healthy cells, bleeding, weakness, fatigue, and infection?

500

What is the appearance of hairy cells under a microscope?

What is hairy projections?

500

What is the role of flow cytometry in diagnosing hairy cell leukemia?

What is to identify specific cell markers?

500

What is the goal of treatment for hairy cell leukemia?

What is remission?

500

What is the name of the first chemotherapy drug used to treat cancer?

What is nitrogen mustard?