Electrophysiology
Antiarrhythmics
100

This is the part of the EKG that corresponds to ventricular repolarization?

What is the T wave?

100

This is the drug of choice for AV block.

What is atropine?

200

This channel is found in SA nodal cells but not ventricular myocytes.

What is the HCN (funny) channel?

200

This is the primary cause of early after depolarizations.

What is a prolonged action potential duration (or long QT interval)?

300

This is the part of the ion channel that plugs the pore of the open channel to stop ion flow.

What is the inactivation gate?

300

This is a class I antiarrhythmic drug (NOT drug class) that increases the action potential duration.

What is quinidine or procainamide (or any class Ia drug)?

400
This is the gating mechanism of inwardly rectifying potassium channels (Kir).

What is polyamine block?

400

This drug class is first-line therapy for catecholamine polymorphic ventricular tachycardia (CPVT).

What are beta blockers?

500

These are TWO channels found in ventricular myocytes that are not in SA nodal cells (must name two).

What are Kir and voltage-gated sodium channels?

500

These two enzyme classes are involved in the metabolism of lidocaine and these are the chemical changes that occur at each step. You must name both classes of enzymes AND both chemical changes.

What are CYP N-dealkylation and amide hydrolysis by amidases?