Week 1
A type of cell communication that occurs when cells are in direct contact with each other and signaling molecules act locally on adjacent target cells.
What is juxtacrine signaling?
This inhibits Factors V and VIII
What is Activated Protein C?
Catabolism of this class of nucleotides leads to uric acid
What are purines?
This complement pathway is activated by the binding of a C1-like complex to carbohydrates on the pathogen's surface
What is the lectin pathway
The peptide that protects MHC II while in the ER has a 60 pack-year history
What is invariant chain smoker?
This GPCR subunit is affected by cholera toxin.
What is Gαs?
Includes macrophages, dendritic cells and B cells
What are Antigen Producing Cells?
This enzyme, inhibited by methotrexate, plays a crucial role in the synthesis of thymidylate by regenerating THF
What is dihydrofolate reductase?
This class of antibody, also known as reaginic antibody, is involved in allergic reactions and is the only immunoglobulin class that binds to basophils and mast cells.
What is IgE?
A frozen treat for patients with abnormal erythrocytes
What is PopSickle Cell Anemia?
This enzyme is inhibited by corticosteroids
What is Phospholipase A2
This is the classic cause of FAP
What is Adenomatous Polyposis Coli?
Pyrimidine synthesis begins with a ring formation between carbamoyl phosphate and this molecule
What is aspartate?
Protein in the thymic medulla that exposes T cells to normal, healthy proteins from all parts of the body.
What is AIRE (Autoimmune regulator
Charlie, Mac, Dennis and the gang try to treat a patient with abnormal BCR-ABL complexes causing Chronic Myeloid Leukemia
What is It's Always Sunny in Philadelphia Chromosome?
The therapeutic index of a drug with an ED50 of 15mg and a TD50 of 90mg
What is 6?
This marks proteins with ubiquitin, signaling them for destruction by the proteasome. This degradation of key proteins ensures orderly cell cycle progression.
What is Anaphase Promoting Complex/Cyclosome (APC/C)
This enzyme catalyzes the rate-limiting step of de novo purine synthesis, converting 5-phosphoribosyl 1-pyrophosphate (PRPP) to phosphoribosylamine.
What is glutamine-PRPP amidotransferase?
This family of pattern recognition receptors, expressed on immune cells, recognizes pathogen-associated molecular patterns (PAMPs) and plays a central role in the innate immune response.
What are Toll-Like Receptors
A shirt appropriate for the end of the 4th week of embryogenesis
What is a neural tube top?
What are IAPs?
Sports Confederation of physically challenged persons based in Luanda, Angola.
What is the African Paralympic Committee?
This condition is associated with defects in salvage pathways.
What is Lesch-Nyhan Syndrome?
This transcription factor, essential for regulatory T cell function, controls the expression of immunosuppressive molecules and helps maintain immune tolerance.
What is FOXP3?
Childhood snack for microbes that secrete endo (but not exo) toxins
What are Teddy Gram-Negative Bacteria?