Gen Med
This chronic illness index includes 19 conditions and predicts 10-year mortality
what is the Charlson Comorbidity Index?
This ECG finding indicates a proximal LAD lesion
what is Wellens’ sign?
This gas transfer abnormality distinguishes emphysema from chronic bronchitis
what is low DLCO?
This cytogenetic translocation defines CML
what is t(9;22) BCR-ABL?
This neurotransmitter deficit causes parkinsonism
what is dopamine?
A high serum osmolal gap (>10) suggests ingestion of one of these two alcohols
what are methanol or ethylene glycol?
This maneuver increases the murmur of hypertrophic cardiomyopathy
what is Valsalva?
The most common cause of bronchiectasis in developed countries
what is cystic fibrosis?
The anticoagulant safe in pregnancy but not renally cleared
what is unfractionated heparin?
This gene mutation causes Huntington’s disease
what is CAG repeat expansion in HTT?
This class of drugs improves survival in both HFrEF and diabetic nephropathy
what are SGLT2 inhibitors?
This ECG pattern — coved ST elevation in V1–V3 with RBBB morphology — is characteristic of this inherited sodium channelopathy.
What is Brugada syndrome?
This autoimmune disease causes both pulmonary hemorrhage and GN
what is Goodpasture’s syndrome?
Warm autoimmune hemolysis is mediated by this immunoglobulin
what is IgG?
This triad (ataxia, ophthalmoplegia, confusion) signals thiamine deficiency
what is Wernicke’s encephalopathy?
The triad of fever, rash, and eosinophilia from drug exposure is known as
what is DRESS syndrome?
The post-MI complication causing new murmur and pulmonary edema within 1 week
what is papillary muscle rupture?
This sleep-related hypoventilation syndrome is due to leptin resistance
what is obesity hypoventilation syndrome?
This vitamin deficiency causes both anemia and subacute combined degeneration
what is B12 deficiency?
This condition presents with progressive ophthalmoplegia, ptosis, and exercise-induced weakness that improves with rest.
What is myasthenia gravis?
This disease presents classically in young women with hypertension, and “string of beads” on angiography
what is fibromuscular dysplasia?
This inherited cardiac condition is caused by mutations in desmosomal proteins such as plakoglobin or desmoplakin and is associated with ventricular arrhythmias and fibrofatty myocardial replacement.
What is arrhythmogenic right ventricular cardiomyopathy (ARVC)?
This rare lung cancer subtype is strongly linked to asbestos exposure but not to smoking.
What is malignant mesothelioma?
This acquired clonal stem-cell disorder is due to a somatic PIGA mutation, leading to complement-mediated hemolysis and venous thrombosis.
What is paroxysmal nocturnal haemoglobinuria (PNH)?
The “hot cross bun” sign on MRI is characteristic of this multisystem neurodegenerative disorder.
What is multiple system atrophy (MSA-C type)?