DNA Basics
DNA Replication
Transcription
Translation
Mutations and DNA Repair
100

This molecule is commonly given the abbreviation DNA. 

What is deoxyribonucleic acid?

100

These short fragments of DNA are created on the lagging strand during DNA replication. 

What are Okazaki fragment?

100

This type of enzyme synthesizes RNA from a DNA template.

What is an RNA polymerase?

100

This organelle, found in the cytoplasm, carries out translation. 

What is the ribosome. 

100

This term refers to a chemical or physical agent that increases the rate of DNA mutation. 

What is a mutagen?

200

These two nucleotides are considered purines. 

What are adenine and guanine?

200

This protein is considered the licensing factor in prokaryotes. 

What is DnaA?

200

This specific enzyme is responsible for synthesizing pre-mRNAs in eukaryotes. 

What is RNA polymerase II?

200

This molecule is responsible for bringing amino acids to the ribosome during translation. 

What is tRNA? 

200

This process involves the reciprocal exchange of DNA between two DNA molecules with similar sequences. 

What is homologous recombination? 

300

In interrupted genes, these sequences are removed from the primary transcript. 

What are introns?

300

This principle of DNA replication was established through the classic Meselson-Stahl experiment. 

What is semiconservative replication? 

300

These DNA sequences position RNA polymerase at the transcription start site and contain the necessary information to initiate transcription. 

What are promoters?

300

These protein factors bind to the small subunit of the ribosome prior to the large subunit joining the complex. 

What are initiation factors?

300

This type of mutation refers to a pyrimidine being swapped for a different pyrimidine or a purine being swapped fora a different purine. 

What is a transition?

400

This intermolecular force is responsible for holding together duplex DNA. 

What is hydrogen bonding?

400

This type of bond is created by DNA polymerase at the active site. 

What is a phosphodiester bond?

400

This protein subunit is required for RNA polymerase to bind to the promoter region in prokaryotes. 

What is the sigma factor?

400

This specific protein factor binds aminoacyl-tRNA in the presence of GTP and brings the aminoacyl-tRNA to the A site of the ribosome. 

What is EF-Tu?

400

These proteins are responsible for resolving Holliday junctions during homologous recombination in E. coli.

What are Ruv proteins? 

500

This type of tightly condensed genetic material is common in centromeric regions. 

What is heterochromatin? 

500

This is the specific gene name of the bacterial protein that adds an RNA primer to the beginning of each Okazaki fragment. 

What is DnaG?

500

This temporary structure is formed during splicing when the 5' end of the intron is cleaved and joined to the branch site. 

What is a lariat?

500

This nucleotide sequence located upstream of the start codon is responsible for positioning the ribosome in prokaryotes. 

What is the Shine-Dalgarno sequence?

500

This name is given to the eukaryotic DNA repair mechanism in which stalled RNA polymerase recruits additional proteins that remove and replace the damaged nucleotide. 

What is transcription coupled nucleotide excision repair?