MTC
What is the difference in function of NADH and NADPH
NADH is usually produced in catabolic processes
NADPH is usually produced in anabolic processes
A RCT is
An interventional COHORT study with a treatment and control arm. It is randomised for confounding
What are the three primary functions of epithelia
Protection Secretion Barrier
What is the function of Oxytocin in women
Uterine contraction during childbirth Milk let down
What is the normal BP for an adult
120/80
What happens to the Km and Vmax during competitive inhibition vs non-competitive inhibition
Competitive: Km increases, Vmax stays the same
Non-competitive: Km stays the same Vmax decreases
What kinds of information should be disclosed to a patient when gaining informed consent 3 points
- Reasonable patient Individual patient Professional standard
What are 3 of 6 features of all living things
MOVEMENT ,Reproduction Responsive Growth Metabolism Differentiation
What is the order of loss of pituitary function in panhypopituitarism
Go Look For the Adenoma GH, LH, FSH, TSH, ACTH, PRL somatotropes, gonadotropes, thyrotropes, corticotropes, lactotropes
What is normal respiration rate
12-16/min
Cystic Fibrosis involves which type of transporter and why does it cause respiratory problems
The channel stops working, so Cl- can't leave the cells and thus water is not drawn out of the cell. Without water the secreted mucous becomes thick and builds up causing infections
What are 2 of the 4 philosophical reasons for maintaining confidentiality
Virtue-based, principal-based, consequentialist based, moral-based
What type of connective tissue is found in the dermis
Dense irregular connective tissue
Name 2 hormones that are permissive with catecholamines
T3,T4, Cortisol
What are the 5 moments of hand hygiene
1. Before touching a patient
2. Before a procedure
3. After a procedure
4. After touching a patient
5. After touching the surroundings
What reaction does alcohol dehydrogenase catalyse:
Substrate and product
ethanol-> acetaldehyde
What are 3 professionalism attributes
Altruism Morality Promotion of public good Integrity Competence
What accessory proteins mediate skeletal muscle contraction
troponin and tropomyosin
Impact of thyroid hormone on fat metabolism
Cholesterol: Decreases plasma cholesterol
Increases lipolysis more than lipogenesis, increased fatty acid release from adipocytes
What details about medication must be asked when taking a history
Generic name, concentration, dose (number), route,
frequency (how often), indication, when commenced
side effects
Name an activation transfer coenzyme
Coenzyme A, Biotin - Activation transfer: covalently bind to substrate to cause catalysis, often involved in the transfer of functional groups
What are the Hippocratic facies and what do they mean
3
- pale face, diarrhoea, sunken eyes, sharp nose, ears cold and drawn in, skin drawn back
With H& E staining, straight purple ECM lines and lacunae are found in which type of connective tissue
Elastic Cartlidge
What are the pumps required in thyroid hormone biosynthesis
NIS: Sodium/Iodide symporter 2Na+ in and one I- in
Pendrin: One iodide into lumen and one Cl- into cell antiporter
Name the parts of SOCRATES
Site Onset Character Radiation Associated Symptoms Time/duration Exacerbating/relieving factors Severity