ACP jeopardy practice 2023

Rheumatology-Antibodies

100

Antibodies characteristic of drug induced lupus 

Anti histone antibodies 

200

Anti-U1RNP antibodies are seen in this rheumatological condition

Mixed connective tissue disease

300

Antibodies seen in Lambert-Eaton syndrome 

antibodies to voltage gated calcium channel receptors

400

Risk for scleroderma renal crisis increases with presence of this class of antibodies

anti-RNA-3 antibodies (other risk factors are use of steroids, diffuse cutaneous systemic sclerosis)

500

Presence of these antibodies in mother with SLE increases risk of congenital heart block in neonates

Anti-Ro and Anti-La (SSa and SSb)

Oncology

100

Medication associated with decreased risk of colorectal cancer after 10 years of daily use

Aspirin (accept NSAIDs)

200

Infectious cause of gastric MALT lymphoma

H. pylori

300

 Eponym for autosomal dominant colonic polyposis syndrome associated with non-gastrointestinal tumors

 Gardner syndrome (accept familial colorectal polyposis)

400

Patients on ATRA (all-trans retinoic acid) for treatment of APML are at risk of developing this syndrome characterized by end organ damage and hypotension

Differentiation syndrome 

500

Most common malignancy seen in kidney transplant recipients 

Cutaneous squamous cell carcinoma 

MSK- physical exam

100

This physical exam maneuver is positive in iliotibial band syndrome 

Noble's test

200

This physical exam finding also known as "barber chair phenomenon" describes an electric shock like sensation upon flexion of neck

Lhermitte's sign

300

Tenderness with palpation over lateral hip prominence is associated with this condition

Greater trochanteric pain syndrome

400

Triad of erythema nodosum, bilateral hilar lymphadenopathy and fever seen in this subtype of sarcoidosis

Lofgren syndrome

500

Splenomegaly is a physical exam finding in this subtype of rheumatoid arthritis 

Felty syndrome

Immunology

100

Anti CD20 monoclonal antibody drug used for treatment of lymphoma

Rituximab

200

This asthma medication has a black box warning to cause depression

Monteleukast

300

This test is performed to rule out risk of hypersensitivity before administration of allopurinol

HLA B*58:01

400

Amyloid fibrils associated with rheumatoid arthritis

AA

500

This variant of Guillain Barre syndrome primarily involves bulbar muscles with no limb weakness

Miller-Fischer syndrome (anti GQ1b antibody syndrome)

Oncology-misc

100

Physical tumor dimension incorporated in the staging of melanoma

Tumor depth

200

This cutaneous lymphoma has cells with atypical nuclei described as "cerebriform"

Mycosis fungoides (accept Sezary syndrome)

300

"Wasabi nose" or nasopharyngeal discomfort is seen with administration of this type of chemotherapeutic agent

Cyclophosphamide

400

This gene testing is done for patients with high risk prostate cancer

BRCA mutation testing

500

Type of antibody associated with paraneoplastic encephalitis also known as NMDA receptor encephalitis 

Anti-Hu antibodies