Acquired CNS Disorders/Degenerative Diagnoses

Spinal cord injury

100

This type of spinal cord injury is characterized by loss of pain, temperature and light touch below a specific dermatome level

Contralateral spinothalamic tract lesion

200

This type of spinal cord injury is characterized by bilateral loss of all modalities and bilateral leg weakness

Complete cord lesion

300

This type of spinal cord lesion may spare sacral sensation

Partial spinothalamic tract lesion

400

This type of spinal cord injury involves loss of all modalities at one or several dermatome levels

Brown-Sequard syndrome (Partial cord lesion)

500

This type of spinal cord injury involves loss of proprioception, discrimnatory touch up to a similar level, limb weakness and pain and temp. below a specific dermatome level

Brown-Sequard syndrome (Partial cord lesion)

Neural Tube Disorders

100

This disorder is the least severe, typically L5-S1 and the meninges don't protrude through the defect

Spinal Bifida Occulta

200

In this disorder the meninges and spinal cord protrude through the defect

Spinal Bifida w/ myelomeningocele

300

In this disorder, the neural tube didn't close entirely, the meninges and nervous tissue protrude through the defect

Spinal bifida w/ myeloschsis  

400

This disorder is characterized by failure of the vertebral arches to fuse in midline

Spinal Bifida 

500

In this disorder, meninges protrude through the defect, typically lumbar

Spinal Bifida Cystica/Meningocele 

Pathology

100

This type of pathology is characterized by an uncontrolled sympathetic response that causes SEVERE HEADACHE, HTN, excessive sweating and an extreme increase in stroke risk

Autonomic Dysreflexia

200

This pathology is characterized by rapidly progressive/degenerative, is a cross-over disease (UMN/LMN), has impact on all body systems and better outcomes in amultidisciplinary clinic

ALS

300

What are the requirements for definite dx of ALS?

UMN + LMN signs in three regions

400

This onset is responsible for 75% of ALS cases 

Limb

- lower limbs (tripping, stumbling, falling)

- upper limbs (buttoning, turning keys)

500

This onset is responsible for 25% of ALS cases

Bulbar

- Speech (slurring, hoarseness, decreased volume)

- difficulty swallowing

- Hypersialorrhea (excessive salivation)

- pseudobulbar affect

Medications

100

These medications are associated with ALS

Riluzole

Edaravone

Relyvrio

Nuedexta

200

These medications are associated with Parkinson's

Levodopa

COMT inhibitors

Dopamine Agonist

MAO B Inhibitors

300

These medications are associated with Multiple Sclerosis

Ocrevis

Tysabri

Tecfidera

Gilenya

ABC's

400

What is a common concern from MS and medications used to treat it

Developing Progressive Multifocal Leukoencephalopathy (PML)

500

This disease attacks the white matter of the brain, caused by a virus infection that targets cells that make myelin, robs the brain of leukocytes and leads to necrosis

Progressive Multifocal Leukoencephalopathy (PML)

Misc.

100

These 3 diseases are affected by damage to the basal ganglia

- Parkinson's 

- Normal Pressure Hydrocephalus

- Huntington's

200

Part of the basal ganglia that controls conscious and proprioceptive movements

Global pallidus

300

Most outer part of the basal ganglia that's involved in speech articulation, addiction, learning and motor control

Putamen

400

Part of basal ganglia that plays a role in dopamine production, controlling movements and causes resting tremors if damaged 

Substantia nigra

500

This part of the basal ganglia is a C-shaped subcortical structure near the thalamus that plays a role in planning execution of movement, reward, motivation, romantic interaction

Caudate nucleus