The pre-renals
Drugs
Transplant
Is it Lupus?
Potpourri
100
The urine sodium expected with any of the pre-renal AKIs
U Na < 20
100
3 biggest AIN culprits
PPI, allopurinol, penicillins
100
Every heart/liver transplant patient gets this type of AKI
ATN
100
The ingredient mixed with cocaine that causes a vasculitis picture
Levimasole
100
Name the crystal and the underlying condition that causes AKI
Uric acid, TLS
200
The most sodium avid state of the body
HRS
200
Mechanism of AKI with acyclovir
acyclovir crystal nephropathy
200
In all solid organ transplants, this commonly used immunosuppressive agent is nephrotoxic
Tacrolimus/prograf
200
The most common glomerular pathology in the world
IgA nephropathy
200
The two non-crystal mechanisms by which hypercalcemia causes AKI
- vasoconstriction
- Acts as a loop diuretic
300
Pathophysiology of CRS
Renal venous congestion = increased renal venousp pressure
300
Anti-hypertensive that can cause a drug induced vasculitis picture
Hydralazine
300
Virus that causes AKI in kidney transplants, but not in native kidneys
BK Virus
300
The lab marker that correlates best with lupus nephritis
anti ds-DNA
300
Ethylene glycol causes AKI via what mechanism?
Calcium oxalate formation
400
HRS Treatment option if they fail the cocktail, and the major side effect to worry about
Terlipressin -> pulmonary edema
400
This antibiotic causes ototoxicity and a ATN like picture
(and surgeons like to hide that they've used it when they call nephrology, as if we won't find out)
Gentamicin
400
The most common infection in all solid organ transplants, and the most common way it causes AKI
CMV - causes diarrhea which causes a pre-renal AKI
400
Linear, IgG staining on immunofluorescence is indicative of this GN
Goodpasture's Syndrome
400
Name the crystal and culprit medication
Sulfa, Bactrim
500
Explain what the rule of 1/3 is for CRS
With diuresis, 1/3 of CRS pts will have worsening renal function, 1/3 will have stable renal function, and 1/3 will have improved renal function.
500
Expected rise in Cr with ACE/ARBs
By 30%
500
For ganciclovir resistant CMV, this medication can be used, but is very nephrotoxic.
Cidofovir
500
Drug of choice for a scleroderma renal crisis
captopril
500
Diets high in rhubarb, nuts, spinach, beets, kiwi can cause AKI via high levels of this compound
oxalate