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Neurotransmission
The Body
Medications
Addictive Substances
Random
100
The neurotransmitter causing pleasure and feeling of reward
What is dopamine
100
Requiring more substance to produce the same effect.
What is tolerance.
100
Purpose of medications during withdrawal
What is symptom management- prevent unnecessary discomfort, reduce cravings, prevent seizures, etc.
100
Opiates are originally/naturally derived from this.
What is the poppy.
100
Unscramble.......... o u p i r e h a.
What is euphoria.
200
Otherwise known as the limbic system (VTA-->nucleus accumbens-->amygdala --->hippocamous)
What is the brains reward system.
200
The liver is able to process alcohol at this rate.
What is 1 standard drink/hour.
200
An example of a benzodiazepine.
What is lorazepam (ativan), clonazepam (Klonopin), diazepam (valium). The "pams"
200
Risk of using percocets, vicodin and T3's.
What is liver toxicity. related to acetaminophen content.
200
Homeostasis.
What is the body's preferred state of natural balance. Dynamic equilibrium. Regulates body temperature, fluid, calcium/bone......neurotransmitters.
300
The brain's main inhibitory neurotransmitter (prevents sending signal)
What is GABA
300
Another word for fibrosis
What is scarring.
300
This medication is toxic to the liver if taken at this amount in a 24h period.
What is acetaminophen (Tylenol); 4000mg/day
300
Major risk of opioid use/CNS depressant effect.
What is overdose related to respiratory depression.
300
Define detoxification.
What is removal of harmful substances/toxins from the body.
400
The brain communicates neuron to neuron by these 2 ways.
What is through chemical and electrical signals
400
Injection use of opioids and stimulants is associated with these two infections.
HIV and Hepatitis C. Also localized infection at site of injection (cellulitis, abscess)
400
Disulfram (antabuse)
What is the medication that helps to prevent relapse to drinking, by causing unpleasant side effects (hangover/flu-like symptoms) when alcohol is ingested.
400
Cocaine, Ritaline, Adderal, Caffeine, amphetamines,
What is examples of stimulants.
400
What was last weeks class on?
What was opioids & the body.
500
Relationship between neurotransmitters GABA (inhibitory) and Glutamate (excitatory) during alcohol withdrawal.
What is that GABA has been increased while drinking alcohol (causing calming/depressive effect on CNS), so glutamate increases to compensate. Then when alcohol is out of the system (ie. withdrawal), glutamate remains high, with no GABA to compensate as it was depleted/"burnt out". High glutamate (excitatory) leads to tremors, anxiety, restlessness, etc.
500
20% of alcohol is absorbed ______, while 80% of alcohol is absorbed _______.
What is in the stomach and in the small intestines.
500
the "ceiling effect" of Buprenorphine, an opioid medication, has this purpose
What is to bind to opioid receptors strongly without fully activating them as much as other agonists (morphine, heroin, oxycodone, etc.) would - that even with increase in dosages would not lead to heightened euphoria or furthered respiratory depression. Therefore is a "replacement" treatment when withdrawing from opioids.
500
Fentanyl is this much more potent than heroin or morphine.
What is 50-100x.
500
ALT (enzyme), AST (enzyme), bilirubin, INR (clotting), albumin level
What is liver function tests (if liver is doing its job)