ETIOLOGY AND PATHOPHYSIOLOGY
WHAT ARE THE THREE CLASSES OF ADRENAL CORTICOSTEROIDS
MINERALOCORTICOIDS, GLUCOCORTICOIDS, ANDROGENS
T/F: PATIENTS WITH ADDISON'S DISEASE WILL EXPERIENCE WEIGHT GAIN AND STRIAE
FALSE; THAT IS SEEN IN CUSHING SYNDROME
WHAT IS THE MAIN COMPLICATION OF ADDISON'S DISEASE
ADDISONIAN CRISIS
WHAT IS THE MOST COMMON DIAGNOSTIC TEST FOR ADDISON'S DISEASE
ACTH STIMULATION TEST
WHAT IS THE TREATMENT GOAL FOR A PATIENT WITH ADDISON'S DISEASE
FLUID & ELECTROLYTE, AND HORMONE REPLACEMENT
WHAT DEMOGRAPHIC IS MOSTLY AFFECTED BY ADDISON'S DISEASE
WHITE WOMEN
WHAT CAUSES HYPERPIGMENTATION IN ADDISON'S DISEASE?
INCREASED B-LIPOTROPIN
WHAT ARE THREE TRIGGERS OF ADDISONIAN CRISIS
STRESS, INFECTION, TRAUMA, SURGERY, ABRUPT WITHDRAWAL OF CORTICOSTEROID THERAPY
WHAT IS THE EXPECTED RESULTS OF THE ACTH STIMULATION TEST FOR A PATIENT WITH ADDISON'S
HIGH ACTH, WITH LITTLE TO NO INCREASE IN CORTISOL
WHY DO WE GIVE LARGE VOLUMES OF IV FLUID?
To reverse hypotension and electrolyte imbalances until BP returns to normal.
WHAT OTHER AUTOIMMUNE DISORDERS DO PATIENTS WITH AUTOIMMUNE ADRENALITIS HAVE?
TYPE 1 DIABETES, AUTOIMMUNE THYROID DISEASE, PERNICIOUS ANEMIA, CELIAC DISEASE
WHERE IS THE HYPERPIGMENTAION USUALLY FOUND ON THE BODY
sun-exposed areas of the body, at pressure points, over joints, and in the creases, especially palmar creases.
WHAT IS THE GOAL OF ADDISONIAN CRISIS TREATMENT
FLUID AND CORTISOL REPLACEMENT
WHAT ARE THE EXPECTED LAB FINDINGS OF A PATIENT WITH ADDISON'S DISEASE
Hyperkalemia
Hypochloremia
Hyponatremia
Hypoglycemia
Anemia
↑ Increased level BUN
Low urine cortisol levels
T/F: WOMEN WITH ADDISON'S DISEASE WILL NEED ANDROGEN REPLACEMENT
TRUE
WHAT IS IT CALLED WHEN ADDISON'S DISEASE PRESENTS WITH OTHER ENDOCRINE PROBLEMS
AUTOIMMUNE POLYGLANDER SYNDROME
HOW DOES ADDISON'S DISEASE AFFECT BLOOD PRESSURE?
Severe lack of cortisol can cause life-threatening low blood pressure
WHEN IS 5% DEXTROSE IN NS SOLUTION PREFERRED
IN HYPOGLYCEMIC PATIENTS
WHY WOULD A PATIENT WITH ADDISON'S DISEASE BE HYPOGLYCEMIC?
Addison's disease is characterized by a deficiency of glucocorticoids, including cortisol, which can lead to decreased glucose production in the liver and decreased glucose uptake in peripheral tissues.
WHAT IS THE EXPECTED DIET FOR PATIENTS WITH ADDISON'S DISEASE?
HIGH PROTEIN AND CARB DIET
WHAT ARE THE OTHER CAUSES OF ADDISON'S DISEASE
tuberculosis, amyloidosis, fungal infections, AIDS, metastatic cancer.
WHY DO PATIENTS WITH SECONDARY ADRENOCORTICAL HYPOFUNCTION NOT EXPERIENCE HYPERPIGMENTATION?
ACTH levels are low.
WHAT DO WE MONITOR IN PTS WITH ADDISONIAN CRISIS
LOC, VITAL SIGNS, I&O, LAB VALUES
WHAT WOULD THE EKG SHOW OF A PATIENT WITH ADDISON'S DISEASE AND WHAT ELECTROLYTE AFFECTS IT?
low voltage and peaked T waves; potassium
T/F: A PATIENT WITH ADDISON'S DISEASE WILL NEED TO INCREASE THEIR CORTICOSTERID DOSE IN STRESSFUL SITUATIONS
TRUE