Molecular Biology
Enzyme that synthesizes RNA from DNA.
What is RNA polymerase?
First antibody produced in primary response.
What is IgM?
Uncontrolled cell growth.
What is neoplasia?
Bradford assay measures this.
What is protein concentration?
Patient with high glucose, polyuria, high HbA1c.
What is diabetes mellitus?
DNA sequence where transcription begins.
What is the promoter?
Immune cells responsible for phagocytosis and antigen presentation.
What are macrophages?
Benign tumors are characterized by this growth pattern.
What is localized/non-invasive growth?
Gel electrophoresis technique that separates DNA by size.
What is agarose gel electrophoresis?
Patient with fever, productive cough, and lobar consolidation on imaging.
What is pneumonia?
Removes introns from pre-mRNA.
What is the spliceosome?
Antibody involved in allergic reactions.
What is IgE?
Tumor suppressor gene often mutated in cancers.
What is p53?
Western blot detects proteins using this.
What are antibodies?
Patient with fever, night sweats, weight loss, Reed-Sternberg cells.
What is Hodgkin lymphoma?
Structure added to the 5’ end of mRNA for stability and translation initiation.
What is the 5’ cap (7-methylguanosine cap)?
Cells that kill virus-infected cells without prior sensitization.
What are natural killer (NK) cells?
Process by which epithelial cells gain mesenchymal, invasive properties.
What is epithelial-to-mesenchymal transition (EMT)?
Chromatography method that separates proteins based on isoelectric point.
What is ion exchange chromatography? (accept: isoelectric focusing if they justify)
Patient with jaundice, elevated ALT/AST, and viral markers.
What is hepatitis?
RNA Pol II termination model involving exonuclease.
What is the torpedo model?
MHC class I presents to this cell type.
What are CD8+ T cells?
Hallmark involving ability to invade and spread.
What is metastasis?
Technique separating proteins by isoelectric point then size.
What is 2D gel electrophoresis?
Patient with petechiae, cyanosis, neck compression signs.
What is asphyxiation?