ADYNOVI [Antihemophilic Factor (Recombinant), PEGylated] is
…the first and only PEGylated treatment with an extended terminal half-life based on the ADVATE product protein from Baxalta, a company with decades-long heritage in hemophilia.
100
What is the highest mountain in Switzerland?
Dufourspitze
100
What decision did the british people take in June 2016?
Brexit
100
What is the t1/2 for Adynovi?
14.3 h (vs 10.4h for Advate)
100
What is biggest competitor for Adynovi?
Elocta
200
ADYNOVI [Antihemophilic Factor (Recombinant), PEGylated] is based on...
.... the manufacturing process of the ADVATE product
200
What is the reasong behind the name "Rigi", the landmark of the canton Zug?
it is the Queen of he mountains
200
How did the Swiss people vot in the poo for or against a basic income?
nealry 77% against
200
What was the dose adminstered and with what frequency in the phase 2/3 for the 109 patients in the prophylaxis arm?
45 +7- 5 Iu/kg twice weekly
200
what is the difference between Elocta and Adynovi?
Elocta`s longer acting is due to binding to an IGg
300
the half -life of ADYNOVI [Antihemophilic Factor (Recombinant), PEGylated] showed a... prologation
1.4 -1.5 fold (compared with Advate).
300
When did Switzerland fail during the soccer european championship in France this summer?
rond of sixteen
300
Where have the olympic games 2016 taken place?
Rio
300
For what does "FAS" and PPAS" stand for?
FAS= full set analysis
PPAS= per protocoll analysis set
(no difference for the number of on demand pateints (17) but FAS prophy= 121, PPAS =101).
300
What is the USP for Sobi?
Convience in the infusion scedule - recommeded every 4 days
400
HOw were the pharmacokinetik parameters for ADYNOVI calculated?
By one-stage clotting and chromogenic assays
400
WHo was able to secure the Swiss Eishockey mastership this year?
Lugano
400
When will the USA vote for a new president?
8th of November
400
what is the mean and median annual bleeding rate for Adynovi int he prophy arm:
-overall?
- joint bleedings?
- spontanous bleedings?